Early in gestation, fetal wounds are capable of healing scarlessly. Scarless healing in the fetus is characterized by regeneration of an organized dermis with normal appendages and by a relative lack of inflammation. Although there is a transition period between scarless and scar-forming repair, scarless healing also depends on wound size and the organ involved. The ability to heal scarlessly, ...

Defective placentation and subsequent placental insufficiency lead to maternal and fetal adverse pregnancy outcome, but their pathologic mechanisms are unclear, and treatment remains elusive. The mildly hypertensive BPH/5 mouse recapitulates many features of human adverse pregnancy outcome, with pregnancies characterized by fetal loss, growth restriction, abnormal placental development, and def...

Nerve lesions at different fetal ages and on the day of birth were used to determine the role of the periphery in establishing territories devoted to representations of different portions of the body surface in rat somatosensory cortex. Transection of the infraorbital nerve (ION), the trigeminal branch that supplies the whisker pad, resulted in a significant reduction in the area within the pri...

conclusions our data showed that inhalation of diazinon during pregnancy increased the hepatocyte area and hepatocyte apoptosis while it decreased the sinusoid area of the fetal liver. materials and methods twenty-five pregnant balb/c mice (25 - 30 gr) were divided into five equal groups in the animal lab of baqiyatallah university of medical sciences, tehran, iran. the normal group was without...

This report considers the equine intrauterine conceptus from the time of entry from the oviduct as a blastocyst to expulsion as a foal. A series of events involving physical interactions between the uterus and conceptus will be highlighted, and the associated morphologic and physiologic aspects will be considered. Most of the events were discovered and characterized by transrectal ultrasonic im...

The placenta plays a key role in regulation of fetal growth and development and in mediating in utero developmental programming. Obesity, which is associated with chronic inflammation and mitochondrial dysfunction in many tissues, exerts a programming effect in pregnancy. We determined the effect of increasing maternal adiposity and of fetal sex on placental ATP generation, mitochondrial biogen...

Reproductive and developmental disorders are the most sensitive toxic effects caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD is thought to produce many, if not all, of these toxic effects by impairing steroidogenesis and/or steroid action during the prenatal or early postnatal stages. However, the mechanism of the antisex steroid effect of TCDD is not well understood. This study rev...

background: fetal heart rate (fhr) extracted from abdominal electrocardiogram (ecg) is a powerful non-invasive method in appropriately assessing the fetus well-being during pregnancy. despite significant advances in the field of electrocardiography, the analysis of fetal ecg (fecg) signal is considered a challenging issue which is mainly due to low signal to noise ratio (snr) of fecg. objective...

OBJECTIVE To determine changes in the incidence of vaginal deliveries, cesarean sections, and forceps deliveries and their potential association with fetal, early neonatal, and perinatal mortality rates over time. METHODS A retrospective study was carried out and the occurrence of deliveries supervised by university services between January 1991 and December 2000 was determined. Data regardin...

BACKGROUND Pregnancy associated malaria is associated with decreased birth weight, but in-utero evaluation of fetal growth alterations is rarely performed. The objective of this study was to investigate malaria induced changes in fetal growth during the 3(rd) trimester using trans-abdominal ultrasound. METHODS An observational study of 876 pregnant women (398 primi- and secundigravidae and 47...