Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. Though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. It has a female predilection and most commonly seen among young Asian people. Patients usually present with a febrile illness and the presence of lymphadeno...

Infections are still an important cause of mortality and morbidity in pediatric cancer patients. Most of the febrile episodes in immunocompromised patients are classified as a fever of unknown origin (FUO) while bacteria are the more frequent causes of documented infections. Viral infections are also feared during chemotherapy but less data are available on their incidence and morbidity. We rev...

BACKGROUND Fever accounts for 70% of all consultations with pediatricians and family physicians. Fever without an identifiable cause (<7 days' duration) and fever of unknown origin (FUO, ≥ 7 days' duration) are particularly challenging clinical situations. METHOD This article is based on a selective literature search for publications containing the term "pediatric fever management," with spec...

OBJECTIVE To identify a set of variables that could discriminate patients with adult-onset periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome from subjects with fever of unknown origin (FUO). METHODS We enrolled 74 adults diagnosed with PFAPA syndrome according to the currently used pediatric diagnostic criteria and 62 additional patients with FUO. After ...

We report on an 83-year-old Japanese woman with adult-onset Still's disease (AOSD), with marked hypercytokinemia (serum levels of ferritin (Fer) and interleukin (IL)-18 were markedly high). On seeing older patients with fever of unknown origin (FUO), particularly Asians, AOSD should be considered. Reduced doses of oral prednisolone following intravenous methylprednisolone (mPSL) therapy caused ...

a 32-year-old end stage renal disease (esrd) woman was scheduled for transplantation. also, she has had fever of unknown origin (fuo), rise of esr and ppd>22 mm. therefore treatment with isoniazid and rifampin was started three months prior to transplantation. she developed allograft dysfunction on week after transplantation. she received a few course pulse therapy (methyl prednisolone), antily...

A 67 year old female presented with generalized weakness, falls and recurrent high grade fevers for 5 6 weeks. Physical findings included high grade temperature, lower extremity weakness and diminished reflexes. An extensive work-up for fever of unknown origin (FUO), including PET-FDG scan, did not yield any occult infectious or neoplastic process. Ultimately a temporal artery biopsy was planne...

One of the most important infectious diseases in the world is Malaria. About half of the world populations are exposed to the risk of the disease. The program for controlling and eradication of Malaria has been being conducted in our country since many years ago. One of the public health problems in the endemic and non-endemic countries is Imported Malaria which can ...

Background: Brucellosis is an important re-emerging zoonosis with a worldwide distribution. It is a common but often neglected disease in India. Objectives: To detect prevalence of brucellosis in clinically suspected cases of Fever of Unknown Origin and to compare the diagnostic efficacy of ELISA and Conventional blood culture. Material And Methods: Blood samples from 100 suspected cases of fev...

FAPA syndrome (periodic fever, aphthous stomatititis, pharyngitis and adenitis) is a relatively new entity described in pediatric patients. In adults, reports of FAPA are limited to rare case reports. The differential diagnosis of FAPA in adults includes Behcet's syndrome, familial Mediterranean fever (FMF), Hyper IgD syndrome and juvenile rheumatoid arthritis (JRA), i.e., adult Still's disease...