نتایج جستجو برای: fgfr4 gene

تعداد نتایج: 1141581  

Journal: :Cancer research 1987
F Ohsawa S Natori

Receptors for tumor-killing factor (TKF) on the surface of murine cells were analyzed using radioiodinated TKF. Not only sensitive cells but also insensitive cells were found to have specific receptors. Among the sensitive cells, no clear relation was observed between the number of receptors on the cell surface and sensitivity to TKF. Compounds affecting microfilaments (cytochalasin B and D) an...

2016
Wenya Zhou Xiaoling Du Fengju Song Hong Zheng Kexin Chen Wei Zhang Jilong Yang

BACKGROUND Malignant peripheral nerve sheath tumors (MPNST) are rare, highly malignant, and poorly understood sarcomas. The often poor outcome of MPNST highlights the necessity of identifying prognostic predictors for this aggressive sarcoma. Here, we investigate the role of fibroblast growth factor receptor (FGFR) family members in human MPNSTs. RESULTS aCGH and bioinformatics analysis ident...

Journal: :international journal of fertility and sterility 0
pouria hossein nia mojtaba tahmoorespur sayyed morteza hosseini mehdi hajian somayyeh ostadhosseini mohammad reza nasiri

background: little is understood about the regulation of gene expression during early goat embryo development. this study investigated the expression profile of 19 genes, known to be critical for early embryo development in mouse and human, at five different stages of goat in vitro embryo development (oocyte, 8-16 cell, morula, day-7 blastocyst, and day 14 blastocyst). materials and methods: st...

Journal: :Cancer research 2011
David L Masica Rachel Karchin

Cooperative dysregulation of gene sequence and expression may contribute to cancer formation and progression. The Cancer Genome Atlas (TCGA) Network recently catalogued gene sequence and expression data for a collection of glioblastoma multiforme (GBM) tumors. We developed an automated, model-free method to rapidly and exhaustively examine the correlation among somatic mutation and gene express...

Journal: :European Journal of Cancer 2022

Background: Hepatocellular carcinoma (HCC), which accounts for up to 90% of all primary liver cancers, is a leading cause cancer mortality worldwide. FGF19 gut secreted endocrine hormone that acts in through its unique receptor FGFR4 and co-receptor KLB, regulate bile acid synthesis hepatocyte proliferation. reported be overexpressed and/or amplified ∼30% HCC. Genomic functional studies have id...

Background Little is understood about the regulation of gene expression during early goat embryo development. This study investigated the expression profile of 19 genes, known to be critical for early embryo development in mouse and human, at five different stages of goat in vitro embryo development (oocyte, 8-16 cell, morula, day-7 blastocyst, and day 14 blastocyst). MaterialsAndMethods Stage-...

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