Risk factors for pancreatic ductal adenocarcinoma (PDAC) progression after surgery are unclear, and additional prognostic factors are needed to inform treatment regimens and therapeutic targets. PDAC is characterized by advanced sclerosis of the extracellular matrix, and interactions between cancer cells, fibrillar collagen, and other stromal components play an integral role in progression. Cha...

Abstract This article investigates the mechanical behavior of polyamide and carbon fiber‐reinforced (CFR) structures produced by Fused Filament Fabrication. CFR improves solid polyamide's tensile strength modulus more than 200% 800%, respectively. The enhancement is highest in parallel raster due to alignment fibers printing direction. compression tests gyroid, honeycomb, Voronoi cellular revea...

Our work discusses the tolerance modeling of an optical fiber that is inserted into a cylindrical alignment bore. We note that some commercial optical simulation software suites have the mechanical tolerance operands entered in Cartesian coordinates and if radial variation is entered as simple X and Y de-centering, there arises a kind of "corner condition" where fiber in the opto-mechanical mod...

A tapered, metal-coated, optical fiber probe will elongate when heated by light input through a fiber. The induced motion can be used for data storage or nanostructuring of a surface. The elongation produced by this alignment-free system is measured with force feedback in a near-field scanning optical microscope (NSOM). The input light intensity controls the elongation magnitude, which ranges f...

We present detailed instructions for constructing and operating an optical trap using a hollow core fiber and two-laser beams. The trap is stable, confining 100-nm to 10-mm particles of a variety of materials for hours of leisurely observation. The trap operates at room temperature and atmospheric pressure, costs less than $1400, and requires no machining. The hollow fiber provides automatic re...

We report a compact light collection scheme suitable for retrofitting a scanning tunneling microscope (STM) for STM-induced light emission experiments. The approach uses a pair of optical fibers with large core diameters and high numerical apertures to maximize light collection efficiency and to moderate the mechanical precision required for alignment. Bench tests indicate that efficiency reduc...

We report on the first demonstration of velocity-matched distributed photodetectors and balanced photodetectors with p-i-n photodetectors. Record-high linear dc photocurrent of 45 mA has been achieved without suffering from thermal damage, thanks to the superior power handling capability of p-i-n photodiodes. A novel fiber alignment technique has been developed to achieve high linear photocurre...

We demonstrate a high sensitivity all­fiber Mach–Zehnder interferometer (MZI) based on radial­aligned liquid crystal (LC) in a hollow optical fiber (HOF). The transmission spectrum of the liquid crystal­filled fiber MZI (LCF­MZI) was measured at different temperatures, and the thermal­induced wavelength shift of the interference spectrum probed. The experimental results indicate that the LC ali...

The microstructural orientation of vascular wall constituents is of interest to scientists and clinicians because alterations in their native states are associated with various cardiovascular diseases. In the arterial media, the orientation of these constituents is often described as circumferential. However, it has been noted that, just below the endothelial surface, the vascular wall constitu...

In this paper we review recent design methodologies for fully dielectric electro-optic sensors that have applications in non-destructive evaluation (NDE) of devices and materials that radiate, guide, or otherwise may be impacted by microwave fields. In many practical NDE situations, fiber-coupled-sensor configurations are preferred due to their advantages over free-space bulk sensors in terms o...