Exhaustive bicycle ergometric exercise in 20 untrained male and female medical students in the age group of 18-25 yrs resulted in significant changes in clotting and prothrombin time, platelet adhesiveness and fibrinolytic activity. Clotting and Prothrombin time were reduced while platelet adhesiveness and fibrinolytic activity were increased in both the sexes.

The effects of phenformin and ethyloestrenol and phenformin and stanozolol on the clinical state, plasma fibrinolytic activity, and fibrinogen-fibrin-related antigen (F.R.-antigen) were compared with placebo in 13 patients with cutaneous vasculitis. Eight patients showed considerable clinical improvement when taking phenformin and an anabolic steroid; an impaired fibrinolytic activity before tr...

Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade the surrounding tissues. Similar to neoplas...

OBJECTIVES As the predominant approach to acute reperfusion for ST segment elevation myocardial infarction (STEMI) in many countries, fibrinolytic therapy provides a relative risk reduction for death of ∼16% across the range of baseline risk. For patients with low baseline mortality risk, fibrinolytic therapy may therefore provide little benefit, which may be offset by the risk of major bleedin...

introduction: the precise time of using percutaneous coronary intervention (pci) after fibrinolytic therapy for maximum efficiency and minimum side effects is still undetermined. therefore, the present study was designed to compare the outcome of myocardial infarction (mi) patients who underwent surgical intervention (angiography and pci) within 48 hours of thrombolytic therapy or after that. m...

Biomaterial Fibrin Clot Structures Stylized fibrin clots are presented in article number 2100988 by Anna Waterhouse and co-workers. Less dense on hydrophobic (right) compared to hydrophilic (left) polystyrene more easily lysed, demonstrating potential for targeted fibrinolytic treatment improved hemocompatible device design.

Androgen deficiency is associated with an increased incidence of cardiovascular disease. There is evidence that thromboembolic disease as well as myocardial infarction in hypogonadic males are mediated by low baseline fibrinolytic activity. Hypogonadism in males is associated with an enhancement of fibrinolytic inhibition via increased synthesis of the plasminogen activator inhibitor PAl 1. On ...