OBJECTIVE To estimate the cost-effectiveness of a treatment strategy for symptomatic uterine fibroids, which starts with Magnetic Resonance-guided Focused Ultrasound Surgery (MRgFUS) as compared with current practice comprising uterine artery embolisation, myomectomy and hysterectomy. DESIGN Cost-utility analysis based on a Markov model. SETTING National Health Service (NHS) Trusts in Engla...

BACKGROUND It has been suggested that an inadequate blood supply caused by uterine fibroids may lead to decreasing fertility. Therefore, a quantitative evaluation of blood flow in the uterus might be a good tool for infertility treatments. For the first step, the ability to perform arterial spin labeling (ASL)-MRI in pelvic organs was examined by measuring blood flow in the uterine muscle layer...

BACKGROUND Transcatheter uterine artery embolisation (UAE) for the treatment of symptomatic fibroids has been performed in several centres in the United States, Western Europe and Asia with promising results. This study reports the authors' experience with UAE at the University Malaya Medical Centre. METHOD Fifty women with symptomatic uterine fibroids who declined surgery were treated by tra...

Uterine leiomyomata (fibroids) are the leading cause of hysterectomy in the United States. Black women have a greater fibroid burden than whites, yet no study has systematically evaluated the growth of fibroids in blacks and whites. We prospectively tracked growth for 262 fibroids (size range: 1-13 cm in diameter) from 72 premenopausal participants (38 blacks and 34 whites). Fibroid volume was ...

Uterine leiomyomas (or fibroids) are the most common tumors in women of reproductive age. Early studies of two familial cancer syndromes, the multiple cutaneous and uterine leiomyomatosis (MCUL1), and the hereditary leiomyomatosis and renal cell cancer (HLRCC), implicated FH, a gene on chromosome 1q43 encoding the tricarboxylic acid cycle fumarate hydratase enzyme. The role of this metabolic ho...

PURPOSE To identify risk factors for the development of intrauterine infection following uterine artery embolization. MATERIALS AND METHODS A retrospective review of uterine artery embolizations (UAE) performed for the treatment of symptomatic fibroids from January 2000 to July 2003 was conducted. With logistic regression and the Fisher exact test, multiple variables were analyzed as predicto...

Uterine fibroids may be encountered with pregnancy and many obstetricians will inevitably confront the dilemma of how best to manage fibroids causing complications in a gravid uterus. We describe two cases of unavoidable caesarean myomectomy and myomectomy performed for the management of complications during pregnancy.

Uterine fibroid or fibromyoma is a very common benign human tumor and the most frequent tumor in the woman’s reproductive system. Uterine fibroids affect millions of women across the world and they are still the most commonly surgically treated. In Romania too, uterine fibroid is the most common reason for hysterectomy, about 60% of cases have this diagnosis preoperatively established. Uterine ...

Uterine fibroids (also known as leiomyomas or myomas) are the most common form of benign uterine tumors. Clinical presentations include abnormal bleeding, pelvic masses, pelvic pain, infertility, bulk symptoms and obstetric complications.Almost a third of women with leiomyomas will request treatment due to symptoms. Current management strategies mainly involve surgical interventions, but the ch...