نتایج جستجو برای: fluctuation hypothesis fh
تعداد نتایج: 247227 فیلتر نتایج به سال:
Coronary artery calcification and family history of myocardial infarction in the Dallas heart study.
OBJECTIVES This study aimed to investigate the independent and joint associations between family history of myocardial infarction (FH) and coronary artery calcification (CAC) with incident coronary heart disease (CHD). BACKGROUND FH and CAC are associated with each other and with incident CHD. It is not known whether FH retains its predictive value after CAC results are accounted for. METHO...
background: different viewpoints exist about lipid screening in all children or only in children with positive family history (fh)of premature cardiovascular diseases (cvds) or hypercholesterolemia. this systematic review and meta-analysis aim to assess the effectiveness of lipid screening in children and adolescents according to the existence of positive fh of cvd risk factors.materials and me...
Familial defective apolipoprotein B-100 (FDB) and familial hypercholesterolemia (FH) are the common causes of monogenic primary hypercholesterolemia. An individual of mixed English and Afrikaner descent with both FDB and the FH Afrikaner-1 low-density lipoprotein receptor mutation was identified in our laboratory. Subsequent analysis of her extended family revealed the presence of heterozygotes...
Familial hypercholesterolemia (FH) causes elevation of low-density lipoprotein cholesterol (LDL-C) in blood and carries an increased risk of early-onset cardiovascular disease. A caveat for exploration of new therapies for FH is the lack of adequate experimental models. We have created a comprehensive FH stem cell model with differentiated hepatocytes (iHeps) from human induced pluripotent stem...
Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevations in total cholesterol (TC) and low density lipoprotein cholesterol (LDLc). Development of FH can result in the increase of risk for premature cardiovascular diseases (CVD). FH is primarily caused by genetic variations in Low Density Lipoprotein Receptor (LDLR), Apolipoprotein B (APOB) or Proprotein C...
While heart rate (fH) has been used as an indicator of energy expenditure, quantitative data showing the relationship between these variables are only available for normothermic animals. To determine whether fH also predicts oxygen consumption ( ) during torpor, we simultaneously measured , fH and subcutaneous body temperature (Tsub) of a hibernator, Gould's long-eared bats (Nyctophilus gouldi,...
BACKGROUND Coronary heart disease (CHD) risk inversely associates with levels of high-density lipoprotein cholesterol (HDL-C). The protective effect of HDL is thought to depend on its functionality, such as its ability to induce cholesterol efflux. MATERIALS AND METHODS We compared plasma cholesterol efflux capacity between male familial hypercholesterolaemia (FH) patients with and without CH...
BACKGROUND Family history (FH) assessment is useful in identifying and managing patients at increased risk for cancer. This study assessed reported FH quality and associations with physician perceptions. METHODS Primary care physicians practicing in two northeastern U.S. states were surveyed (n = 880; 70% response rate). Outcome measures of FH quality were extent of FH taken and ascertaining ...
Light states relevant to the $\chi^{(2)}$ comb generation in optical microresonators possess typically dual backgrounds for coupled first-harmonic (FH) and second-harmonic (SH) envelopes. Stability and/or instability of these is crucial realization stable combs also an efficient SH generation. We explore properties their cases FH pumping resonator. In contrast parameteric oscillation, controlle...
BACKGROUND Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl), which may be due to familial hypercholesterolemia (FH). Lifelong LDL cholesterol elevations in FH mutation carriers may confer coronary artery disease (CAD) risk beyond that captured by a single LDL cholesterol measurement. OBJECTIVES This study ass...
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