After undergoing initial reconstructive surgery for hypoplastic left heart syndrome performed between August 1985 and March 1989, 59 patients (age range 3 to 27 months, mean 13.8 +/- 4.5) underwent elective cardiac catheterization in anticipation of a modified Fontan procedure. Five important hemodynamic and anatomic features considered to be components of successful reconstructive surgery were...

INTRODUCTION The Fontan procedure is an intervention that helps to correct single ventricle physiology. There are many known long-term complications of 'Fontan physiology'. However, the occurrence of renal abscess in such patients has not yet been reported in the literature. The first generation of adults has now undergone the procedure and it is necessary to be aware of the long-term outcomes ...

Background. Lessons learned during the developme f a novel hybrid approach have resulted in a reli eproducible alternative treatment for hypoplastic l eart syndrome (HLHS). Herein we report our res sing this hybrid approach in a uniform risk cohort Methods. This is a review of prospectively collec ata on patients treated for HLHS using a hybrid roach (n 40) between July 2002 and June 2007. T yb...

The Fontan procedure has become a generic term to define a surgical procedure that orients the systemic venous return directly to the pulmonary arteries, and has been used as a palliative operation for pulmonary atresia, tricuspid atresia, double inlet ventricle and complex single ventricle. The earliest type of Fontan procedure was a simple atriopulmonary anastomosis between the right atrium a...

BACKGROUND Although the surgical results of the modified Fontan operation continues to improve, there are various advantages and disadvantages in terms of the post operative condition associated with the Fontan modifications. Late morbidity and mortality are mainly due to arrhythmias, thromboembolic complications, systemic venous hypertension and infective endocarditis. We reported our experien...

OBJECTIVES The study sought to identify factors associated with increased risk of thrombosis after Fontan. BACKGROUND The Fontan procedure is the culmination of staged palliation for patients with univentricular physiology. Thrombosis is an important complication after this procedure. METHODS An international multicenter randomized controlled trial of acetylsalicylic acid versus warfarin fo...

Protein losing enteropathy (PLE), defined as severe loss of serum protein into the intestine, occurs in 4-13% of patients after the Fontan procedure and carries a dismal prognosis with a five year survival between 46% and 59%. Chronically raised systemic venous pressure is thought to be responsible for the development of PLE in these patients, with perhaps superimposed immunological or inflamma...

The Valsalva maneuver was performed during cardiac catheterization in 9 patients who had undergone a Fontan operation (Fontan group) and in 10 control subjects. The Fontan group had higher right atrial (RA) pressure (16 f 1 vs 4 f 0.5 mm Hg, p <O.OOi), lower cardiac index (2.5 f 0.1 vs 3.7 f 0.2 liters/min/m*, p <0.05), lower stroke index (32 f 2 vs 44 f 2 ml/beat/m*, p <0.05), and higher syste...

BACKGROUND Few studies have described the neuropsychological outcomes and frequency of structural brain or genetic abnormalities in adolescents with single ventricle who underwent the Fontan procedure. METHODS AND RESULTS In a cross-sectional, single-center study, we enrolled 156 subjects with single ventricle, mean age 14.5±2.9 years, who had undergone the Fontan procedure. Scores in the ent...