background: many efforts have been undertaken until now to find an alternative approach to packed red cell tranfusion in major β-thalassemia. augmentation of fetal hemoglobin by hydroxyurea has proved to be less effective in this condition as compared to sickle cell anemia, probably due to molecular heterogeneity of the former disease. hydroxyurea efficacy and its relation to xmn1 polymorphism ...

background: mutations in β -globin gene may result in β-thalassemia major, which is one of the most common genetic dis­or­ders in iran and some other countries. knowing the beta-globin mutation spectrum improves the efficiency of prenatal diagno­sis in the affected fetuses (major β-thalassemia) of heterozygote couples. methods: couples with high hemoglobin a 2 and low mean corpuscular volume we...

flaxseed oil is known as a functional oil because of the high content of α-linolenic acid; therefore, the aim of this research was to investigate some physicochemical properties of iranian extra virgin flaxseed oil (evfo) and the impact of the refining stages before deodorization on these properties. fatty acid composition, peroxide and anisidine values, free fatty acids, crystallization point,...

The genus Haplophyllum, which belongs to the Rutaceae family, includes 18 species in Iran. In this study, after collecting plant material, botanical identification and suitable drying, the essential oils from aerial parts of Haplophyllum robustum Bge. were extracted by three different isolation techniques, conventional hydrodistillation (HD), microwave-assisted hydrodistillati...

Isoflavone occurs abundantly in leguminous seeds in the form of glycoside and aglycone. However, isoflavone glycoside has anti-nutritional effect and only the free type is beneficial to human health. In the present study we identified a β-glucosidase from thermophilic Neosartorya fischeri P1, termed NfBGL1, capable of efficiently converting isoflavone glycosides into free isoflavones. The gene,...

exo-Methylene-β-lactams were synthesized in two steps from commercially available 3-bromo-2-(bromomethyl)propionic acid and reacted with arene diazonium salts a Heck-type arylation the presence of catalytic amounts Pd(OAc)2 under ligand-free conditions. The products, arylidene-β-lactams, obtained high yields as single isomers. β-hydride elimination step Pd-catalyzed coupling reaction proceeds e...

We consider computations of a Turing machine under noise that causes violations of the transition function. Given an upper bound β on the size of bursts of faults, we construct a Turing machine M(β ) subject to faults that can simulate any fault-free machine under the condition that the time between bursts is lowerbounded by O(β 2).

The two-dimensional one-component logarithmic Coulomb gas is mapped onto a nonhermitian fermionic field theory. At β = 2, the field theory is free. Correlation functions are calculated and a perturbation theory is discussed for extending to other β. A phase transition is found at the mean-field level at large β. Some results are extended to spaces of constant negative curvature.

AIMS/INTRODUCTION To investigate the clinical and anthropometrical parameters that are associated with non-exercise activity thermogenesis that is composed of basal energy expenditure (BEE) and diet-induced thermogenesis (DIT) in patients with diabetes. MATERIALS AND METHODS Body composition was assessed using bioelectrical impedance, and BEE and DIT were measured using indirect calorimetry i...