background: gap-junctional intercellular communication (gjic) is implicated in physicological processes and it is vitally important for granulosa cell (gc) differentiation and oocyte growth. we investigated the expression of connexin 43 (cx43), a gap junctional protein, in normal and androstenedione-induced polycystic ovary (pco), the effects of androstenedione on cx43 expression, gjic and prog...

Objective: To evaluate the microleakage at junction between amalgam-composite resin restorations using different bonding systems. Material and Methods: In this in-vitro study, standard class II cavities were prepared on 40 human maxillary premolars. The axial gingival floor depths of 2 mm 1 below (cementoenamel junction), respectively. samples divided into 4 groups (n = 10). all groups, a layer...

Voltage-gated sodium channels (NaCh) are colocalized with isoforms of the membrane-skeletal protein ankyrin G at axon initial segments, nodes of Ranvier, and postsynaptic folds of the mammalian neuromuscular junction. The role of ankyrin G in directing NaCh localization to axon initial segments was evaluated by region-specific knockout of ankyrin G in the mouse cerebellum. Mutant mice exhibited...

Avila and Molina [1] introduced the notion of generalized weak structures which naturally generalize minimal structures, generalized topologies and weak structures and the structures α(g),π(g),σ(g) and β(g). This work is a further investigation of generalized weak structures due to Avila and Molina. Further we introduce the structures ro(g) and rc(g) and study the properties of the structures r...

CONTEXT Esophagogastric junction adenocarcinoma has an aggressive behavior, and TNM (UICC) staging is not always accurate enough to categorize patient's outcome. OBJECTIVES To evaluated p53, cyclin D1 and Bcl-2 immunoexpressions in esophagogastric junction adenocarcinoma patients, without Barrett's esophagus, and to compared to clinicopathological characteristics and survival rate. METHODS ...

Recently, graphitic carbon nitride (g-C 3 N 4 ), a polymeric semiconductorhas been widely used as low-cost, stable, and metal-free visible-light-active photocatalyst in the sustainable utilization of solar energy, such water splitting, organic photosynthesis, environmental remediation, which has attracted world wide attention from energy relative fields. Base on analysis structure theoretical c...

Tetanus neurotoxin (TeNT) and botulinum neurotoxins (BoNTs; from A to G) are metalloproteases that act on nerve terminals to prevent exocytosis. They are extensively exploited for the study of cellular physiology. Moreover, BoNTs are also employed in clinical neurology for the treatment of several disorders characterized by hyperexcitability of peripheral nerve terminals. This review summarizes...

The percentage of fertilized eggs from chicken hens inseminated with turkey semen is very low (Warren & Scott, 1935; Quinn, Burrows & Byerley, 1937; Asmundsen & Lorenz, 1957; Wisoki & Soller, 1968), but it can be considerably increased by depositing the spermatozoa beyond the utero-vaginal junction (Kempenich-Pinto, Schindler, Bornstein & Baroutchieva, 1970). The question arose whether the inse...

We proposed a new three-way DNA junction-driven strand displacement mode and fabricated an aptamer-based label-free fluorescent sensing platform on the basis of this mechanism. Assembling the aptamer sequence into the three-way DNA junction makes the platform sensitive to the target of the aptamer. A label-free signal readout method, split G-quadruplex enhanced fluorescence of protoporphyrin IX...

The RuvC protein of Escherichia coli catalyzes the resolution of recombination intermediates during genetic recombination and the recombinational repair of damaged DNA. Resolution involves specific recognition of the Holliday structure to form a complex that exhibits twofold symmetry with the DNA in an open configuration. Cleavage occurs when strands of like polarity are nicked at the sequence ...