Marginal ulcers are a known complication after Rouxen-Y gastric bypass, with a variable incidence of .6–16% [1,2]. Initial therapy involves elimination of the inciting risk factors [3] and medical management with a proton pump inhibitor and sucralfate therapy [4]. Although most marginal ulcers will heal with such treatment, approximately one third of patients will require operative intervention...

PURPOSE The role of peritoneal washing cytology in determining further treatment strategies after surgery for gastric cancer remains unclear. One reason for this is the fact that optimal procedures to increase the accuracy of predicting peritoneal metastasis have not been established. The aim of this study was to evaluate the efficacy of cytology using samples harvested from two different abdom...

by blocking H /K -ATPase at the terminal steps of gastric acid secretion process. So, PPIs are assumed that their potency of gastric antisecretory effect is stronger than that of the histamine H2-receptor antagonists. Omeprazole, one of the PPIs, was discovered by Fellenius et al. and is widely used in treatment of peptic ulcer, gastro esophageal reflux disease and eradication of Helicobacter p...

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

Complications of laparoscopic adjustable gastric banding (LAGB) are well documented including migration, erosion, prolapse, infection, pouch dilatation, and gastric perforation. Band prolapse within the first 5 years after LAGB is observed in about 5% of cases, requiring an operative procedure. Here we report our experience of endoscopic treatment of band prolapses. From December 2007 to Decemb...

WIZRTHER, J. LAWRENCE, AND FRANKLIN HOLLANDER. Potassium in mecholyl-stimulated gastric secretion in the dog. Am. J. Physiol. 202(4) : 72 1-724. 1962. Previous work indicated that K concentration ([K]) of gastric juice rises abruptly after histamine injection, concomitantly with acid efflux. Using Heidenhain and vagal pouch dogs, these experiments (26 in all) were repeated with mecholyl and his...

The purpose of this study was to investigate the circadian changes in the abomasal secretions (quantities of juice, enzymes and electrolytes) of the preruminant calf. The gastric juice was collected every hour from five calves fitted with an innervated abomasal pouch and given milk twice daily, with a 7-h interval between the morning and the evening meals. The amounts of gastric secretions prod...

Proglumide suppressed neither phase III activity nor propagation of interdigestive migrating contractions (IMC) in the gastrointestinal tract. Furthermore, proglumide did not inhibit the gastric motor activity stimulated by pentagastrin, however, it suppressed the pH in Pavlov pouch stimulated by pentagastrin in the interdigestive state. On the contrary, in the digestive state, proglumide did n...

We examined the effects of YM020 (3-cyanomethyl-2-methyl-8-[(3-methyl-2-butenyl)oxy]-imidazo[1,2- a]pyridine), a novel H+,K(+)-ATPase inhibitor, on gastric acid secretion and experimental gastroduodenal lesions in rats and dogs. Intraduodenal, subcutaneous and oral YM020 inhibited basal gastric acid secretion in pylorus-ligated rats with ED50 values of 9.1, 9.1 and 9.5 mg/kg, respectively. Oral...