OWING to the association between alcohol and chronic pancreatitis in man' there has,been considerable interest in the effect of alcohol upon gastro-entero pancreatic (GEP) hormones. Previous estimations of GEP hormones following oral alcohol ingestion have shown raised serum gastrin concentrations in response to 18 per cent and 15 per cent ethanol in man (Becker, Reeder and Thompson2), and Stra...

on the 7th May 1925, with a typical history of chronic duodenal ulcer, extending over 12 years. Within recent months the symptoms of pyloric obstruction had been increasing. He was operated on on the 8th of May. There was found a very chronic ulcer on the anterior surface of the first part of the duodenum, with great thickening, and a considerable amount of stenosis. Posterior gastrojejunostomy...

BACKGROUND AND AIM Ten years ago we published a study describing the 6-month outcome of 33 outpatients with typical gastro-oesophageal reflux disease symptoms and pH-metry proven excess gastro-oesophageal reflux but without endoscopical evidence of oesophagitis, currently referred to as patients with gastro-oesophageal reflux disease without oesophagitis. We now present an update of that report...

Nigella sativa (N. sativa) (Family Ranunculaceae) is a widely used medicinal plant throughout the world. It is very popular in various traditional systems of medicine like Unani and Tibb, Ayurveda and Siddha. Seeds and oil have a long history of folklore usage in various systems of medicines and food. The seeds of N. sativa have been widely used in the treatment of different diseases and ailmen...

An investigation of water absorption from the small intestine after abdominal surgery has produced more detailed information on the effect of trauma on the motility of the gastro-intestinal tract. Whereas after trauma the equilibration of tritiated water given by the oral and colonic routes is retarded, given by the jejunal route it is normal.

Introduction: The incidence rate of gastric erosions and ulcers in diabetic patients are higher due to failure of mucosal antioxidant defense and maintain enough blood flow. The present study evaluated the gastro-protective effect of sodium hydrosulfide (NaHS) against indomethacin-induced gastric lesions in diabetic rats. Methods: In order to test anti-ulcer activity of NaHS against indomet...

KB 95 (Sandoz) is a new derivative of the pyrazolone series which has certain pharmacological similarities to phenylbutazone (Figure), though with a reported lower incidence of gastro-intestinal ulceration in the guinea-pig. Analgesic and anti-inflammatory properties have been demonstrated in mice. It is also said to have a weak antispasmodic effect on smooth muscle and to reduce emotional tens...

OBJECTIVE To measure the relative risks of adenocarcinomas of the oesophagus and gastro-oesophageal junction associated with measures of obesity, and their interactions with age, sex, gastro-oesophageal reflux symptoms and smoking. DESIGN AND SETTING Population-based case-control study in Australia. PATIENTS Patients with adenocarcinomas of the oesophagus (n = 367) or gastro-oesophageal jun...