Background: Aim was to evaluate the differences in platelet count and indices between pregnant women with gestational diabetes mellitus (GDM) apparently healthy women.Methods: A cross-sectional study performed 68 GDM (cases) (controls) after 24 weeks of gestation. The groups were compared terms demographic, clinical laboratory characteristics including indices.Results: Mean volume (MPV) (p=0.00...

CONTEXT Women with previous gestational diabetes mellitus (pGDM) are at high risk of developing type 2 diabetes mellitus in the future. The role of adipokines in women with pGDM has not been established. OBJECTIVE We investigated whether circulating adipokine concentration is associated with abnormal glucose homeostasis in women with pGDM. DESIGN, SETTING, PATIENTS, AND MAIN OUTCOME MEASURES:...

The various strategies to diagnose gestational diabetes mellitus (GDM), starting from O'sullivan, followed by numerous opinions and recommendations and up to the recently published International association of diabetes and pregnancy study groups criteria, have been and still are the subject of extensive and ongoing debate, since the 1960s, and holding, fiercely than ever, nowadays. In this revi...

OBJECTIVE A cross-sectional institutional-based study was undertaken to know the prevalence of Gestational Diabetes Mellitus (GDM) among Indian pregnant women. SUBJECTS AND METHODS 325 pregnant women were screened for evidence of diabetes who were previously not known to be diabetic. They underwent 75 g, 2 hour, oral glucose tolerance test (OGTT). Chi-square test was done for statistically as...

BACKGROUND Gestational diabetes mellitus (GDM) is a disease often manifests in mid to late pregnancy with symptoms including hyperglycemia, insulin resistance and fetal mal-development. The C57BL/KsJ-Lep (db/+) (db/+) mouse is a genetic GDM model that closely mimicked human GDM symptoms. Resveratrol (RV) is a naturally existing compound that has been reported to exhibit beneficial effects in tr...

Background: Weight gain during pregnancy is of great concern for most women and obstetricians because its possible consequences. This exists gestational weight that exceeds what recommended by the Institute Medicine associated with many maternal fetal complications. While excessive (GWG) modifiable risk factors Gestational Diabetes Mellitus (GDM) notably, obesity overweight conditions, there a ...

OBJECTIVES To evaluate gamma-glutamyltransferase (GGT), alanine transaminases (ALT) and aspartate transaminases (AST) levels and prevalent gestational diabetes mellitus (GDM). DESIGN AND METHODS Random plasma glucose, GGT, ALT and AST and the 50-g glucose challenge test were done on antenatal women followed by diagnostic 3-point 75-g oral glucose tolerance test within two weeks. GDM was diagn...

We aim to determine the frequency of preeclampsia (PE) spectrum disorders among subjects with diabetes by subtype: Type 1 mellitus (T1DM); 2 DM (T2DM); gestational diet controlled (A1GDM); medication GDM (A2GDM); and hyperglycemia in early pregnancy. hypothesized a higher rate PE severe features those T1DM T2DM.

Zinc transporter 8 genetic variant SLC30A8 has been associated with postpartum risk of type 2 diabetes among women with gestational diabetes mellitus (GDM). Gestational weight gain is one of the strongest risk factors for postpartum hyperglycemia. We assessed the interaction between type 2 diabetes-associated SLC30A8 rs13266634 and gestational weight gain on 1-5 years of postpartum glycemic cha...