We present detailed microscopic simulations of high-energy cosmic-ray air showers penetrating high-altitude ice layers that can be found at the polar regions. use a combination CORSIKA Monte Carlo code and Geant4 simulation toolkit, focus on particle cascade develops in to describe its most prominent features. discuss impact layer total number particles function depth shower, we give general pa...

In this note we present an update of the validation of Geant4 hadronic physics against the ATLAS pixel 2001 test-beam data. Furthermore, we also report the comparison with Fluka simulation, using the same Geant4 geometry, navigation and digitization.

The Geant4-based Monte Carlo model for Heavy-Ion Therapy (MCHIT) was extended to study the patterns of energy deposition at sub-micrometer distance from individual ion tracks. Dose distributions for low-energy (1)H, (4)He, (12)C and (16)O ions measured in several experiments are well described by the model in a broad range of radial distances, from 0.5 to 3000 nm. Despite the fact that such dis...

Stereo mini-jet cells will be indispensable components of a future ee linear collider central tracker such as JLC-CDC. There is, however, no official Geant4 solid available at present to describe such geometrical objects, which had been a major obstacle for us to develop a full Geant4-based simulator with stereo cells built in. We have thus extended Geant4 to include a new solid (TwistedTubs), ...

In order to assess the feasibility of spallation driven fission and transmutation, we have simulated proton induced neutron production using GEANT4, initially benchmarking our simulations against published experimental neutron spectra produced from a thick lead target bombarded with 0.5 and 1.5 GeV protons. The Bertini and INCL models available in GEANT4, coupled with the high precision (HP) ne...

Brain metastases develop frequently in patients with breast cancer, and present a pressing therapeutic challenge. Expression of vascular cell adhesion molecule 1 (VCAM-1) is upregulated on brain endothelial cells during the early stages of metastasis and provides a target for the detection and treatment of early brain metastases. The aim of this study was to use a model of early brain metastasi...

Monte Carlo (MC) modelling is widely used in the field of single photon emission computed tomography (SPECT) as it is a reliable technique to simulate very high quality scans. This technique provides very accurate modelling of the radiation transport and particle interactions in a heterogeneous medium. Various MC codes exist for nuclear medicine imaging simulations. Recently, new strategies exp...

The modelling of Cherenkov based detectors is traditionally done using Geant4 toolkit. In this work, we present another method on Python programming language and Numba high performance compiler to speed up the simulation. As an example take one Forward Proton Detectors at CERN LHC - ATLAS (AFP) Time-of-Flight, which used reduce background from multiple proton-proton collisions in soft hard diff...

GEANT4 is an effective and comprehensive tool capable of realistically modeling the optics of scintillation and Cerenkov detectors and their associated light guides. This is founded on GEANT4’s unique capacity of commencing the simulation with the propagation of a charged particle and completing it with the detection of the ensuing optical photons on photo sensitive areas, all within the same e...