Colloidal gels consisting of oppositely charged nanoparticles are increasingly utilized for drug delivery and tissue engineering. Meanwhile, cell membrane-coated nanoparticles are becoming a compelling biomimetic system for innovative therapeutics. Here, we demonstrate the successful use of cell membrane-coated nanoparticles as building blocks to formulate a colloidal gel that gelates entirely ...

Red cells from hereditary pyropoikilocytosis (HPP) are unstable and more susceptible than normal to thermal damage in vitro. We have investigated whether or not the HPP instability results from alterations in spectrin assembly in the membrane. We identified the nearest membrane protein neighbors employing oxidative crosslinking by intermolecular disulfide couplings. We subsequently separated th...

This paper describes the in vitro formation and characterization of perfusable capillary networks made of human umbilical vein endothelial cells (HUVECs) in microfluidic devices (MFDs). Using this platform, an array of three-dimensional (3D) tubular capillaries of various dimensions (50-150 μm in diameter and 100-1600 μm in length) can be formed reproducibly. To generate connected blood vessels...

Mouse peritoneal macrophages have been studied in vitro after ingestion of treated rat, rabbit, or sheep erythrocytes. Under light microscopy, phagocytic vacuoles persist up to 24 h. Macrophages lose benzidine reactivity about 5 h after red cell ingestion, and they become prussian blue positive at 2 days. Ultrastructural studies show little or no ferritin in control macrophages not fed erythroc...

Copper sulfate was given to male rabbits intraperitoneally and the copper concentrations in the plasma, red cells and EtOH-CHCl3 treated fraction of the cells were determined. The concentration of copper in the plasma increased markedly and in the red cells increased slightly after administration of 1 mg copper/kg of body weight, while the copper level in the EtOH-CHCl3 treated fraction remaine...

In the past forty years considerable progress has been achieved on the knowledge of human blood as a non-Newtonian shear-thinning suspension, whose initial state, that is at rest (stasis) or at very low shear rates, has a gel-like internal structure which is destroyed as shear stress increases. The main goal of this communication is to describe the role of geometrical aspects during RBC (red bl...

The investigation of two thermal properties of red cells throws some light on whether sickling is a process involving the crystallization of a relatively insoluble hemoglobin. These properties are the specific heat and the heat of compression, both of which would be expected to become numerically less if the hemoglobin of the red cell were to crystallize. In the case of paracrystalline rat red ...

Sunscreen is a preparation that contains chemical compounds can absorb, scatter or reflect sunlight hits the skin so it be used to protect function and structure of human from damage caused by sunlight. In field pharmacology, dragon fruit peel as an antioxidant free radical scavenger. This study aims determine SPF value red (Hylocereus lemairei (Hook) Britton & Roose) extract gel at concent...

Red palm olein, which is rich in β carotene, has the potential as an animal fat replacer for formulation of healthy processed meat products. However, it mainly composed saturated fatty acid, should be reduced by combining with unsaturated acid-rich vegetable oil. Canola oil was mixed red olein order to get benefits from both. The emulsion gel made up and canola at 30/70 (w/w) optimized using a...