نتایج جستجو برای: gene expression signature
تعداد نتایج: 1655967 فیلتر نتایج به سال:
INTRODUCTION Previous observations suggest that active systemic juvenile idiopathic arthritis (sJIA) is associated with a prominent erythropoiesis gene-expression signature. The aim of this study was to determine the association of this signature with peripheral blood mononuclear cell (PBMC) subpopulations and its specificity for sJIA as compared with related conditions. METHODS The 199 patie...
introduction: g-proteins have an important role in the cell signaling of numerous receptors. the situation of g-proteins in health and disease and their critical role in the development of diabetic side effects is an interested scientific field. here, the changes in the expression of g-protein subunits (gαi, gαs and gβ) were evaluated in hyperglycemic situation of pc12 cells as a cellular model...
background: to evaluate vdr gene variation and its interaction with immune regulatory molecules in osteoporosis. methods: totally 205 pre and postmenopausal women were recruited in the study. after an overnight fast, peripheral blood was taken and centrifuged to sprat serum for measurement of serum parathyroid hormone, 25 hydroxyvitamin d, osteocalcin and cross laps. the fok i polymorphism in ...
asthma is a chronic inflammatory disorder of the airways. the stress is a factor for asthma which indicates a disorder in the function of communicational mediators of nervous and immunological systems such as neurotransmitters. a study indicated that blood serotonin concentration increases in asthmatic patients. other study indicates that one kind of the serotonin receptors, named 5ht...
an important step in considering of gene expression data is obtained groups of genes that have similarity patterns. biclustering methods was recently introduced for discovering subsets of genes that have coherent values across a subset of conditions. the las algorithm relies on a heuristic randomized search to find biclusters. in this paper, we introduce biclustering las algorithm and then appl...
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