The XPD protein is a vital subunit of the general transcription factor TFIIH which is not only involved in transcription but is also an essential component of the eukaryotic nucleotide excision DNA repair (NER) pathway. XPD is a superfamily-2 5'-3' helicase containing an iron-sulphur cluster. Its helicase activity is indispensable for NER and it plays a role in the damage verification process. ...

The medial collateral ligament (MCL) is commonly injured in the setting of anterior cruciate ligament (ACL) injuries. Because the MCL has better healing capacity than the ACL, the general perception is that MCL injuries can be treated conservatively. Treating these injuries conservatively, however, can lead to residual valgus laxity. Furthermore, it delays time to surgery, which prevents acute ...

In this paper, we investigate a single-server Poisson input queueing model, wherein arrivals of units are in bulk. The arrival rate of the units is state dependent, and service time is arbitrary distributed. It is also assumed that the system is subject to breakdown, and the failed server immediately joins the repair facility which takes constant duration to repair the server. By using suppl...

the management of machine replacement (specifically tractors) is one of the most critical factors for performing field operations on time. therefore, tractor repair and maintenance costs must be accurately predicted. this research was carried out to evaluate the use of the regression technique in predicting tractor repair and maintenance costs. the study was conducted using empirical data on 60...