BACKGROUND Controversy surrounds prostate-specific antigen (PSA) testing for prostate cancer screening, especially among elderly men aged 75 and older. This study examines whether patient age results in differential use of PSA testing and if organizational attributes such as communication, stress, decision making, and practice history of change predict PSA testing among men aged 75 and older. ...

This study uses simulated data to compare two methods of calculating Differential Test Functioning (DTF): Raju’s DFIT, a parametric method that measures the squared difference between two Test Characteristic Curves (Raju, van der Linden & Fleer, 1995), and a variance estimator based on the Mantel-Haenszel/Liu-Agresti method, a non-parametric method enabled in the DIFAS (Penfield, 2005) program....

INTRODUCTION We performed a systematic review of the literature on preputial reconstruction (PR) during hypospadias repair to determine the cumulative risk of preputial skin complications and the influence of PR on urethroplasty complications, namely, fistula formation and overall reoperation rate of the repair. MATERIALS AND METHODS A systematic search of the literature published after 06/19...

Numerous studies have examined the empirical evidence concerning the influence of demographic and socio-economic factors influencing child immunization, but no documentation is available which shows the actual impact of antenatal care (ANC) visits on subsequent child immunization. Therefore, this paper aims to examine the net impact of ANC visits on subsequent utilization of child immunization ...

BACKGROUND It has been speculated that amoxicillin use could be associated with dental enamel defects. OBJECTIVE To assess the association between dental fluorosis, one of the most common developmental tooth enamel defects, and amoxicillin use during early childhood. DESIGN, SETTING, AND PARTICIPANTS As participants in the Iowa Fluoride Study, subjects were followed up from birth to 32 mont...

OBJECTIVES (1) Assess the population-level probability of prenatal diagnosis and termination of pregnancy for fetal anomaly for four major congenital heart defects; (2) Examine, using population-based data, the relation between timing of (prenatal vs postnatal) diagnosis and risk of infant (ie, < 1 year) mortality for four major congenital heart defects (CHDs). DESIGN Population-based cohort ...

INTRODUCTION Streptococcus pneumoniae remains a major global health problem and a leading cause of death in children worldwide. The factors that influence development of pneumococcal sepsis remain poorly understood, although increasing evidence points towards a role for genetic variation in the host's immune response. Recent insights from the study of animal models, rare human primary immunodef...

Predisposition to psoriasis is known to be affected by genetic variation in HLA-C, IL12B and IL23R, but other genetic risk factors also exist. We recently reported three psoriasis-associated single nucleotide polymorphisms (SNPs) in the 5q31 locus, a region of high linkage disequilibrium laden with inflammatory pathway genes. The aim of this study was to assess whether other variants in the 5q3...

The results of previous Iranian studies on the protective effect health insurance catastrophic expenditures (CHE) are inconsistent. Therefore, aim this meta-analysis was to summarize all existent evidence. We searched international and scientific databases for relevant literature. Using a Mantel–Haenszel random-effects model, pooled odds ratios (OR) were calculated. Subgroup meta-analyses perfo...

INTRODUCTION The aim of this quantitative systematic review/meta-analysis was to compare the treatment outcomes of mineral trioxide aggregate (MTA) and calcium hydroxide (CH) in pulpotomy of human primary molars. The focused PICO question was "in case of pulp exposure in vital primary molars, how does MTA pulpotomy compare to CH in terms of clinical/radiographic success?" METHODS AND MATERIAL...