نتایج جستجو برای: genetic recombination
تعداد نتایج: 646787 فیلتر نتایج به سال:
Recombination initiates at double-stranded DNA breaks and at single-stranded DNA gaps. These DNA strand discontinuities can arise from DNA-damaging agents and from normal DNA replication when the DNA polymerase encounters an imperfection in the DNA template or another protein. The machinery of homologous recombination acts at these breaks and gaps to promote the events that result in gene recom...
This paper investigates the influence of recombination and selfadaptation in real-encoded Multi-Objective Genetic Algorithms (MOGAs). NSGA-II and SPEA2 are used as example to characterize the efficiency of MOGAs in relation to various recombination operators. The blend crossover, the simulated binary crossover and the breeder genetic crossover are compared for both MOGAs on multi-objective prob...
The problem of inferring the population structure, linkage disequilibrium pattern, and chromosomal recombination hotspots from genetic polymorphism data is essential for understanding the origin and characteristics of genome variations, with important applications to the genetic analysis of disease propensities and other complex traits. Statistical genetic methodologies developed so far mostly ...
Recombination varies greatly among species, as illustrated by the poor conservation of the recombination landscape between humans and chimpanzees. Thus, shorter evolutionary time frames are needed to understand the evolution of recombination. Here, we analyze its recent evolution in humans. We calculated the recombination rates between adjacent pairs of 636,933 common single-nucleotide polymorp...
Human immunodeficiency virus type 1 (HIV-1) exhibits a high level of genetic variation generated by frequent mutation and genetic recombination during reverse transcription. We have measured HIV-1 recombination rates in T cells in one round of virus replication. It was recently proposed that HIV-1 recombines far more frequently in macrophages than in T cells. In an attempt to delineate the mech...
The problem of inferring the population structure, linkage disequilibrium pattern, and chromosomal recombination hotspots from genetic polymorphism data is essential for understanding the origin and characteristics of genome variations, with important applications to the genetic analysis of disease propensities and other complex traits. Statistical genetic methodologies developed so far mostly ...
The problem of inferring the population structure, linkage disequilibrium pattern, and chromosomal recombination hotspots from genetic polymorphism data is essential for understanding the origin and characteristics of genome variations, with important applications to the genetic analysis of disease propensities and other complex traits. Statistical genetic methodologies developed so far mostly ...
Genetic male sterility is controlled by one pair of ressesive allele (aa) in sugar beet. This trait is used in most breeding programes. The exsistance of the character in a line or population facilitates transfer of important trait to the breeding material (for example resistance to plant disease). Also, it is possible to increase genetic diversity of monogerm populations by using genetic ma...
Genetic male sterility is controlled by one pair of ressesive allele (aa) in sugar beet. This trait is used in most breeding programes. The exsistance of the character in a line or population facilitates transfer of important trait to the breeding material (for example resistance to plant disease). Also, it is possible to increase genetic diversity of monogerm populations by using genetic ma...
In genetic algorithm, the most commonly used recombination operator involves two parents to produce offspring. A few attempts to study the effect of using multi-parent recombination in genetic algorithm have been reported in the literatures [1][3]. The rationale is to bias the recombination with more parents to improve the performance. In evolution strategies, a recombination operation was firs...
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