نتایج جستجو برای: genomic

تعداد نتایج: 115648  

2016
Stefania Benonisdottir Asmundur Oddsson Agnar Helgason Ragnar P Kristjansson Gardar Sveinbjornsson Arna Oskarsdottir Gudmar Thorleifsson Olafur B Davidsson Gudny A Arnadottir Gerald Sulem Brynjar O Jensson Hilma Holm Kristjan F Alexandersson Laufey Tryggvadottir G Bragi Walters Sigurjon A Gudjonsson Lucas D Ward Jon K Sigurdsson Paul D Iordache Michael L Frigge Thorunn Rafnar Augustine Kong Gisli Masson Hannes Helgason Unnur Thorsteinsdottir Daniel F Gudbjartsson Patrick Sulem Kari Stefansson

Adult height is a highly heritable trait. Here we identified 31.6 million sequence variants by whole-genome sequencing of 8,453 Icelanders and tested them for association with adult height by imputing them into 88,835 Icelanders. Here we discovered 13 novel height associations by testing four different models including parent-of-origin (|β|=0.4-10.6 cm). The minor alleles of three parent-of-ori...

Journal: :Cell 2003
Serge Gravel Stephen P. Jackson

In the September 26 issue of Science, McMurray and Gottschling (2003) report that aged yeast cells display high rates of loss of heterozygosity. Furthermore, they show that this reflects an impaired ability to correctly detect and repair DNA double-strand breaks. These results provide insights into how aging can engender genomic instability in eukaryotic cells.

Journal: :Antimicrobial agents and chemotherapy 2015
Dae Hun Kim Kwan Soo Ko

To investigate the presence and structure of AbaR-type genomic islands (GIs) in non-Acinetobacter baumannii isolates, a total of 155 non-baumannii Acinetobacter isolates from a South Korean hospital were analyzed. GIs were found in three Acinetobacter nosocomialis and two Acinetobacter seifertii isolates. Their structures were similar to those in A. baumannii isolates from Asian countries, incl...

Journal: :cell journal 0

sperm dna is known to contribute one half of the genomic material to the offspring. the integrity of sperm dna is important in fertilization, embryonic and fetal development, and postnatal child well being. the nature has created multiple barriers that allow only the fittest sperm to reach and fertilize an oocyte. however, assisted reproductive techniques (art), like ivf and icsi, may allow spe...

It is essential to identify and determine the properties of native plants as natural genetic resources. The present study was performed to identify the Mindium (Michauxi) laevigata species using molecular and biochemical procedures such as genomic DNA extraction, sequencing, and antioxidant capacity and protein content determination at both vegetative and generative phases in various parts of t...

ژورنال: علوم آب و خاک 2002
ماهرخ فلاحتی رستگار, , امیر دریایی, , بهروز جعفرپور, ,

This study was carried out on the biochemical aspects of chickpea cultivars and the genomic behavior of A. rabiei pathotypes 4 and 6 in four parts: 1) Determining the number of resistant genes in chickpea native cultivars, 2) Comparing the variation of sodium and potassium electrolytes concentrations in noninfected and infected seedling stems of resistant and susceptible cultivars, 3) Studyin...

Abass Daei Naser Ahmad Shavakhi Hasan Shojaei, Mohammad Mehdi Aslani, Peyman Adibi Reza Khashei,

Objective(s) Resistance to antimicrobial agents, particularly metronidazole and clarithromycin, is frequently observed in Helicobacter pylori and may be associated with treatment failure. This resistance rate varies according to the population studied. The aim of this study was to assess the pattern of antimicrobial resistance of H. pylori isolates from dyspeptic patients in Isfahan. Material...

ژورنال: Medical Laboratory Journal 2012
Babavalian H, , Mirnejad R, , Mousazade moghadam M, , Shakeri F, ,

Abstract Background and objectives: Genomic DNA extraction of bacterial cells is of processes performed normally in most biological laboratories therefore, various methods have been offered, manually and kit, which may be time consuming and costly. In this paper, genomic DNA extraction of Staphylococcus aureus was investigated using some laundry detergent brands available in Iran to achieve ...

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