One case of giant-cell arteritis involving the female genital tract of a post-menopausal woman is reported. The patient was a 75 year-old female, who presented anemia, fatigue, weight loss and a palpable abdominal mass. A hysterectomy and bilateral salpingo-oophorectomy proved multiple uterine leiomyomas. The uterus, ovaries and tubes unexpectedly revealed extensive giant-cell arteritis of smal...

Malignant transformation of conventional giant cell tumor of bone is rare and usually occurs with irradiation. This article describes a case of malignant transformation of a giant cell tumor 15 years after initial curettage and bone graft. A 35-year-old man was admitted to the hospital with a recurrent giant cell tumor of the distal femur. On presentation, the patient reported the insidious ons...

BACKGROUND Giant cell arteritis typically involves the temporal arteries, but can involve other cranial arteries. Temporal artery biopsy is the mainstay for the diagnosis of giant cell arteritis; however, biopsy may be problematic if giant cell arteritis involves other cranial arteries that are inaccessible for sampling. In these situations, magnetic resonance angiography is a useful, non-invas...

Giant cell-rich osteosarcoma is an extremely rare variant of conventional osteosarcoma. It accounts for only 1%-3%. undifferentiated high-grade sarcoma with numerous osteoclast-like giant cells. also contains variable amount tumor osteoid. This article aims to present a case involving the right knee joint in young man.

AIM To examine the possible influence of the MHC class II antigens alleles in the formation of the multinucleate aggressive giant cell tumour of bone. METHODS HLA class II antigen alleles were investigated in eight white patients from north east England with confirmed diagnosis of giant cell tumour of bone. All had locally aggressive, immunophenotypically HLA-DR negative giant cell tumours. ...