Abstract Basal cell carcinoma (BCC) is the most common skin cancer. However, BCC on scrotum very rare, with an incidence of 0.03%. Giant BCC, in which tumour larger than 5 cm, has also been reported as a rare variant. Here, we report 71‐year‐old male giant and review similar cases English. None four scrotum, including present case, showed lymph node or distant metastasis. Wide local excision wa...

 Objective(s): Lymph node metastases are the most significant prognostic factor in localized non-small cell lung cancer (NSCLC). Identification of the first nodal drainage site (sentinel node) may improve detection of metastatic nodes. Extended surgeries, such as lobectomy or pneumonectomy with lymph node dissection, are among the therapeutic options of higher acceptab...

Research on tumor-induced lymphangiogenesis has predominantly focused on alterations and abnormal growth of peritumoral and intratumoral lymphatic vessels. However, recent evidence indicates that lymphangiogenesis of sentinel lymph nodes might also contribute to cancer progression. In clinical oncology, the sentinel lymph nodes play an important r...

objectives: presence/absence of cervical lymph node metastasis plays a critical role in prognosis and survival of patients with oral squamous cell carcinoma (scc). this study was designed to assess the diagnostic accuracy of computed tomography (ct) scan for detection of cervical lymph node metastasis in oral scc in comparison with histopathological analysis after neck dissection methods: in th...

Nasopharyngeal carcinoma (NPC) is a head and neck malignant tumor rare throughout most of the world but common in Southeast Asia, especially in Southern China. Flotillin-2 (Flot-2) is not only an important component of cellular membrane, but also involves in various cellular processes such as membrane trafficking, T cell and B cell activation, regulation of several signaling pathways associated...

discoidin domain receptor (ddr) is a new member of the receptor tyrosine kinase family. there are two isoforms of discoidin domain receptor (ddr), ddr1 and ddr2. these receptors play a major role in the adhesion, motility and cell proliferation. due to the important role of ddr2 in the development of tumor extension, this receptor is pivotal in the field of carcinogenesis. the aim of this study...

The acral regions of the limbs of Asians are predisposed to develop malignant melanoma, but giant-sized acral melanoma has not been previously reported in the Asian population. Giant-sized melanoma implies aggressive tumor invasion and so it is more difficult to achieve a therapeutic cure. A 56-year-old woman presented with a giant acral melanoma of the left thumb with concomitant bone destruct...

currently, somatic cell count (scc) and bacterial culture are considered as the gold standard of detecting subclinical mastitis. mastitis leads to proliferation of lymphocytes in the supramammary lymph nodes and subsequent enlargement of ipsilateral lymph node. ultrasonography can be used to survey these changes. a portable ultrasound machine with a 2-5 mhz convex transducer was used to identif...

introduction: there is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (i and ii) breast cancer patients. usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. in this study we evaluated this issue in our patients. methods: 40 patients with the clinical dia...