PURPOSE To compare the clinical features of glaucoma patients who present at a rural hospital in North Eastern Ghana and an urban hospital in the capital city of Accra. METHODS This is a multi-center retrospective case series involving records of newly diagnosed glaucoma patients with emphasis on primary open angle glaucoma (POAG). Information collected included basic demographic data, intrao...

Glaucoma management aims to preserve patients' quality of life by halting progressive visual loss. Intraocular pressure reduction is the pivotal strategy: we establish a "target" pressure based on extent of visual damage, threat to visual performance, risk profile for further damage, pre-treatment pressure levels, family history and a patient's life expectancy. Once an acceptable treatment regi...

This paper proposes a computer aided decision support system for an automated detection of glaucoma in monocular fundus images. Identification of Glaucoma using fundus images involves the measurement of the size, shape of the Optic cup and Neuroretinal rim. Optic Cup detection is a challenging task because of the interweavement of cup with the blood vessels. A new color model technique based on...

Glaucoma is the second leading cause of blindness worldwide. To examine the relationship between angle closure and the retinal vessel diameter in Chinese adults, we conducted Handan Eye Study (HES), a large population-based cross-sectional study, which enrolled 6830 participants >30 year-old living in 13 randomly selected villages of Yongnian County. After adjusting for age, gender, spherical e...

Contrast sensitivity has been measured in patients with glaucoma and ocular hypertension, the latter graded into high, medium, and low risk clinical groups. Measurements were made centrally and peripherally at 10 degrees, 15 degrees, 20 degrees, and 25 degrees off-axis at each of the four meridians 45 degrees, 135 degrees, 225 degrees, and 315 degrees. A sine wave grating of 1.9 cycles/degree, ...

purpose : glaucoma following penetrating keratoplasty (pk) continues to be a serious problem that may ultimately become sight threatening. knowledge of the risk factors for development of glaucoma following pk, such as preexisting glaucoma, pseudophakia, aphakia, and previous pk, can limit the occurrence and improve the outcome of the keratoplasty. the management of postkeratoplasty (post-pk) g...

Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...

Background: Immune reactions have been reported to be involved in the destruction of retinal ganglion cells (RGCs) in glaucoma. Objective: To investigate the role of major histocompatibility complex class I-related chain A and B (MICA and MICB) molecules in the pathogenesis of glaucoma. Methods: Aqueous humor and serum samples from 15 glaucoma patients and 45 patients with cataract, undergoing ...