From a gleam in Alan Turing’s eye in the 1940s, machine intelligence took root as an academic discipline in the 1950s; was cultivated in the 1960s; matured in the 1970s; and spread seed in the 1980s, which took root and bore fruit in a myriad companies in the 1990s. Newquist is a business reporter who covered the field during the 1980s when academic researchers went commercial in one of the 198...

In the current issue of JAMIA, Friedman and Parrish have crafted an insightful and provocative call for the Population Health Record writ large. This paper contributes in an important way to the literature and appears at a propitious time in our nation’s health policy history. Furthermore, it is appropriate for JAMIA in that the AMIA Board first called for such a development in 1997. The author...

In the early 1960s a live BBC television broadcast on Parkinson's disease showed the moment of cessation of tremor in a patient undergoing stereotactic surgery. The importance of the physical sign not only in diagnosis but also, together with knowledge of anatomy, in understanding pathophysiology was made clear and a future addiction to physical signs primed in at least one viewer. Subsequent m...

Lester J. Reed, a pioneer in the field of biochemistry, died peacefully in Austin, Texas on January 14, 2015 at the age of 90. Lester Reed was born in New Orleans on January 3, 1925. He showed an early interest in chemistry, having his own laboratory in a shed under his boyhood home. He received his Bachelors of Science from Tulane in 1943, where he worked with William Shive, and earned his doc...

and the physical. If you want to understand the fundamental and universal properties of a computational process, study the abstract algorithm and prove a theorem about it. If you want to know how the process really works, implement the algorithm as a program and measure the running time (or another quantity of interest). This distinction between the abstract model and the physical artifact exis...

Network centrality is an important determinant of alliance performance. However, estimating how each member's affects performance challenging because the end market might value partner's contribution differently. We solve this empirical question with a two-sided matching model that accounts for partners' endogenous selection and estimates effect side's input quality on implement method in novel...