The distribution and biochemical diversity of neuroglial cells in the avian optic tectum were analyzed using immunohistochemical techniques. Polyclonal and monoclonal antibodies were employed to define the distributions and localizations of four proteins that are considered to be glial-specific in the mammalian central nervous system: glutamine synthetase, carbonic anhydrase-C, glial fibrillary...

Introduction We aimed to map and synthesize the available evidence on neuron-specific biomarkers related COVID-19. Methods A systematic review qualitative mapping synthesis was performed (PROSPERO-CRD42021266995). Searches were conducted in PubMed Scopus, complemented by manual search (July 2021). included observational studies of any design assessing neurological adult patients (>18 years; ...

Papillary glioneuronal tumor (PGNT) is a low-grade biphasic that composed of glial fibrillary acidic protein (GFAP)-positive cells and synaptophysin-positive neurons. We report case PGNT occurring in the right occipital lobe 48-year-old woman who presented with acute headache left homonymous hemianopsia, latter which was difficult to distinguish from malignant brain tumors because peritumoral e...

Purpose To develop an ex vivo explant system using multiphoton microscopy and digital volume correlation to measure the full-field deformation response to intraocular pressure (IOP) change in the peripapillary sclera (PPS) and in the optic nerve head (ONH) astrocytic structure. Methods Green fluorescent protein (GFP)-glutamate transporter-GLT1 (GLT1/GFP) mouse eyes were explanted and imaged w...

This is the report of a mandibular neuroectodermal/ewing sarcoma in an 8-year-old male cross breed dogthat is unique because of tumor origin location. Pedunculated, ulcerative, firm 6.0 × 4.0 × 5.5 cm tumor masseffaced the bone at the rostral part of the mandible and had a white-sanguineous color at cross sectionappearance. Histopathologically, small round blue cell tumor was diagnosed. Immunoh...

Neurons have inherent competence to regrow following injury, although not spontaneously. Spinal cord injury (SCI) induces a pronounced neuroinflammation driven by resident microglia and infiltrating peripheral macrophages. Microglia are the first reactive glial population after SCI and participate in recruitment of monocyte-derived macrophages to the lesion site. Both positive and negative infl...

The intermediate filament network of astrocytes includes Glial fibrillary acidic protein (Gfap) as a major component. Gfap mRNA is alternatively spliced resulting in generation of different protein isoforms where Gfapα is the most predominant isoform. The Gfapδ isoform is expressed in proliferating neurogenic astrocytes of the developing human brain and in the adult human and mouse brain. Here ...