We introduce a covariance cleaning method which works well in the very high-dimensional regime, i.e. when there are many more assets than data points per asset. This opens way to unconditional reactive portfolio optimization not enough calibrate dynamical conditional models, happens, for example, new appear market. The is k-fold boosted version of Bootstrapped Average Hierarchical Clustering pr...

BACKGROUND Previously we reported that decreased postischemic functional recovery was associated with increased DNA fragmentation in the aged myocardium. Magnesium-supplemented potassium (K/Mg) cardioplegia ameliorated DNA fragmentation and enhanced post-ischemic functional recovery. We hypothesized that K/Mg cardioprotection might involve either an RNA- or a protein-dependent mechanism. METH...

in this paper we emphasize the importance of questioning the global validity of significant concepts underpinning global health policy. this implies questioning the concept of global health as such and accepting that there is no global definition of the global. further, we draw attention to ‘quality’ and ‘empowerment’ as examples of world-forming concepts. these concepts are exemplary for the g...

1-Nearest Neighbor with the Dynamic TimeWarping (DTW) distance is one of the most effective classifiers on time series domain. Since the global constraint has been introduced in speech community, many global constraint models have been proposed including Sakoe-Chiba (S-C) band, Itakura Parallelogram, and Ratanamahatana-Keogh (R-K) band. The R-K band is a general global constraint model that can...

In this paper, the construction of Euler systems of cyclotomic units in a general global function fields is explained. As an application, an analogue of Gras' conjecture in a global function field is proved. 1. I n t r o d u c t i o n and n o t a t i o n s Kolyvagin [7] introduced his remarkable Euler systems to prove important new results on ideal class groups of nmnber felds. This method was ...