OBJECTIVE To determine the best predictors of total postprandial glycemic exposure and peak glucose concentrations in nondiabetic humans. RESEARCH DESIGN AND METHODS Data from 203 nondiabetic volunteers who ingested a carbohydrate-containing mixed meal were analyzed. RESULTS Fasting glucose and insulin concentrations were poor predictors of postprandial glucose area above basal (R2 = approx...

The role of glucose 6-P (glucose 6-phosphate) in regulating the activation state of glycogen synthase and its translocation is well documented. In the present study, we investigated the effects of glucose 6-P on the activation state and compartmentation of phosphorylase in hepatocytes. Glucose 6-P levels were modulated in hepatocytes by glucokinase overexpression or inhibition with 5-thioglucos...

gestational diabetes mellitus (gdm) is one of the important problems in pregnant women. this study conducted to determine association the level of serum glucose with fetal-maternal complications of gestational diabetes with insulin therapy. this study has been conducted as an existing data study, so medical records of all pregnant women with gdm that have been treated with insulin during 2 year...

Background: Diabetes mellitus type 2 with dyslipidemia is a common disease. Previous studies suggest that chemical constituent present in pinus eldarica (P. eldarica) nut posesess antioxidant properties and positively affect glucose metabolism. However blood glucose and cholesterol lowering effects of P. eldarica nut have not been studied so far. Objective: The present study was undertaken to...

The mechanism of activation of the phosphoglucomutase reaction by the coenzyme, cu-glucose 1,6-diphosphate, was studied by Leloir et al. (1)) Sutherland et al. (2)) and Jagannathan and Luck (3). In 1954, Najjar and Pullman (4) showed that the active, phosphorylated form of the enzyme interacted with glucose l-phosphate to form the coenzyme and the inactive, dephosphorylated enzyme, and that the...

conclusions it can be concluded that the nettle extract can reduce blood glucose levels in diabetic mice, at least partly, by influencing the glut2 gene expression in mice liver. results the results showed that the nettle extract significantly decreased high levels of blood glucose (p < 0.001). the nettle extract also had a preventive effect on decrease in body weight. in addition, the results ...

Abstract Objectives Our study aims to assess the impact of lockdown during coronavirus disease 2019 pandemic on glycemic control and psychological well-being in youths with type 1 diabetes. Methods We compared metrics same period 2019. The was evaluated Test Anxiety Depression. Results analyzed 117 adolescents (87% Multiple Daily Injections 100% were flash glucose monitoring/continuous monitori...

We questioned the general view that contraction-induced muscle glucose transport only depends on stimulation frequency and not on workload. Incubated soleus muscles were electrically stimulated at a given pattern for 5 min. Resting length was adjusted to achieve either no force (0% P), maximum force (100% P), or 50% of maximum force (50% P). Glucose transport (2-deoxy-d-glucose uptake) increase...