The biochemical effects in the livers of male rats of prolonged administration of the experimental hepatocarcinogen nafenopin, a hypolipidemic agent and peroxisome proliferator, were com pared to those of another experimental liver carcinogen, phéno barbital, which acts as a neoplasm promoter. Feeding of nafen opin, 0.03 mmol/kg basal diet for up to 24 weeks increased the numbers of hepatic pe...

The biochemical effects in the livers of male rats of prolonged administration of the experimental hepatocarcinogen nafenopin, a hypolipidemic agent and peroxisome proliferator, were com pared to those of another experimental liver carcinogen, phéno barbital, which acts as a neoplasm promoter. Feeding of nafen opin, 0.03 mmol/kg basal diet for up to 24 weeks increased the numbers of hepatic pe...

BACKGROUND Cyanate is a uremic toxin formed principally via spontaneous urea biodegradation. Its active isoform, isocyanate, is capable of reaction with proteins by N and S carbamoylation, which influences their structure and function. Sulfurtransferases implicated in anaerobic cysteine transformation and cyanide detoxification belong to the enzymes possessing SH groups in their active centers....

Numerous known risk factors for atrial fibrillation (AF) exist, but few studies have investigated the link between gastrointestinal and liver disorders. Through a variety of pathways, hepatic conditions can increase both prevalent incident AF. According to numerous studies, dysfunction plays significant role in pathogenesis fibrillation. So, this review article aimed give an overview how functi...

Bu çalışmada Kurşun (Pb)’un sublethal derişimlerinin ve Pb + NTA (Nitrilotriasetik asit) karışımının, 7 21 gün süreyle, etkisine bırakılan tatlısu balığı O. niloticus’un kas karaciğer dokularındaki bazı enzim aktiviteleri oksidatif stres düzeyi incelenmiştir. Parametreler, otoanalizatör cihazlarla ölçülmüştür. Elde edilen veriler neticesinde; dokusunda total oksidan (TOS), indeksi (OSİ) düzeyle...

Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abste...

Because 1% to 9% of people without symptoms have elevated liver enzymes, extensive evaluation of all abnormal test results would expose many patients to undue risks and expenses. On the other hand, failure to evaluate minor liver enzyme elevations could mean missing the early diagnosis of potentially treatable disorders. This review discusses likely causes of elevated aminotransferase, alkaline...

Ravi Dhingra, Philimon Gona, Thomas J. Wang, Caroline S. Fox, Ralph B. D'Agostino, Sr and -Glutamyl Transferase and Risk of Heart Failure in the Community γ Serum Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2010 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis...