We investigated the effect of FeSO4 on phagocytosis-associated, increased oxidative metabolism via the hexose monophosphate shunt, with special attention to its effect on H2O2 levels. The availability of glutathione peroxidase and glutathione reductase for H2O2 disposal and hexose monophosphate shunt stimulation also are evaluated. The results show an impairment of phagocytosis-associated hexos...

We investigated the relationship between H2O2 metabolism and the senescence process using soluble fractions, mitochondria, and peroxisomes from senescent pea (Pisum sativum L.) leaves. After 11 d of senescence the activities of Mn-superoxide dismutase, dehydroascorbate reductase (DHAR), and glutathione reductase (GR) present in the matrix, and ascorbate peroxidase (APX) and monodehydroascorbate...

The aim of this study was to characterize the effect of decreased 2-cysteine peroxiredoxin (2-CP) on the leaf anti-oxidative system in Arabidopsis. At three stages of leaf development, two lines of transgenic Arabidopsis mutants with decreased contents of chloroplast 2-CP were compared with wild type and a control line transformed with an empty vector. Glutathione contents and redox state were ...

This study was conducted to investigate the metabolic defensive mechanism in the larvae of African palm weevil (Rynchophorus phoenicis) administered with dichlorvos (2,2-dichlorovinyl dimethylphosphate) solution. Bioassay experiment with dichlorvos was conducted on the larva and glutathione-utilizing enzyme activities were determined in the major organs: fat body, gut, and head of R. phoenicis ...

OBJECTIVE Our goal was to assess the effects of weight loss on antioxidant enzymes of red blood cells and it's relation with vitamins A, E and C intake in 30 obese women. SUBJECTS AND METHODS General information, anthropometric measurements, 3-day food recall, and fasting blood samples were collected from 30 obese women at the beginning of the study and after 3 months intervention. Weight los...

BACKGROUND AND AIM Lansoprazole, a benzimidazole derivative, is a widely-used proton-pump inhibitor. In addition, it has been reported to have an independent gastroprotective action. Since free radicals and antioxidant mechanisms appear to counter-act tissue-related injury, we studied the effect of lansoprazole on oxidative stress in acid-ethanol gastric injury. As this drug is metabolized in t...

The effects of double stress environment i.e. lead (heavy metal) and NaCl (saline) on the activity of antioxidant enzymes in Vigna radiata seedling were studied. The antioxidant activities of enzymes, i.e of superoxide dismutase, catalase, ascorbate peroxidase, guaiacol peroxidase, glutathione reductase and their activity proportions were examined. Superoxide dismutase, ascorbate peroxidase, gu...

Studies of serum glutathione reductase activity in thislaboratory prompted an attempt to demonstrate glutathione oxidase in the serum. The oxidation of reduced glutathione in the sera of patients with various diseases does not differ from normal sera. Preheating the serum and addition of cytochrome c does not effect the oxidizing capacity of the serum. The ability of serum to oxidize reduced gl...