Glycyrrhizic acid (GA) is the main active component of licorice root, which has been known in traditional medicine since ancient times. It a molecule composed hydrophilic part, two glucuronic molecules, and hydrophobic glycyrrhetinic acid. GA, when subjected to hydrolysis, releases 18?- 18?-glycyrrhetinic acids. Glycyrrhetinic most responsible for pharmacological activities licorice. GA reporte...

A triterpene saponin, glucoglycyrrhizin, was isolated from a glycyrrhizin-deficient strain 83-555 of Glycyrrhiza uralensis (Leguminosae), and the structure was determined by chemical and spectral data to be 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl]-glycyrrhetinic acid. Since this saponin has a 2'-O-β-D-glucopyranosyl moiety instead of the 2'-O-β-D-glucuronopyranosyl moiety of glycyr...

The physicochemical properties (pH and osmolarity), ingredients, and impurities containing in compound glycyrrhizin injections (eight items) marketed in China were compared with those in bland-name drug (Stronger Neo-Minophagen C injection). Glycyrrhizin (GZ), glycine (Gly), and l-cysteine (CysH) as the ingredients, moreover, glycyrrhetinic acid (GA), 3-monoglucuronyl-glycyrrhetinic acid (MGGA)...

Herbs have been used as a form of traditional medicine since ancient times. Licorice is one the herbs that has long medicine. This plant contains different compounds, such glycyrrhizin, 18??glycyrrhetinic acid, glabrins A and B, isoflavones, showing various pharmacological activities. Pharmacological experiments shown extracts pure compounds this species exhibit broad biological properties, inc...