We compare the single-particle plasmonic sensitivity of silver and gold nanorods with similar resonance wavelengths by monitoring the plasmon resonance shift upon changing the environment from water to 12.5% sucrose solution. We find that silver nanoparticles have 1.2 to 2 times higher sensitivity than gold, in good agreement with simulations based on the boundary-elements-method (BEM). To excl...

Plasmon resonance energy transfer (PRET) has been widely applied in the detection of bio-recognition, heavy metal ions and cellular reactions with high sensitivity, based on the overlap between the plasmon resonance scattering band of nanoparticles and the absorption band of the surface-modified chromophore molecules. Previous sensors based on PRET were all implemented on gold nanospheres with ...

A core–shell heterostructure consisting of plasmonic gold nanorods and porphyrinic metal–organic frameworks is synthesized as a promising platform to combine photodynamic therapy photothermal for enhanced tumor treatment.

We present the development of an analytical model that can be used for the rational design of a biosensor based on shifts in the local surface plasmon resonance (LSPR) of individual gold nanoparticles. The model relates the peak wavelength of light scattered by an individual plasmonic nanoparticle to the number of bound analyte molecules and provides an analytical formulation that predicts rele...

BACKGROUND In lung cancer, the efficacy of conventional chemotherapy is limited due to poor drug accumulation in tumors and nonspecific cytotoxicity. Resolving these issues will increase therapeutic efficacy. METHODS GNR-Dox-Tf-NPs (gold nanorod-doxorubicin-transferrin-nanoparticles) were prepared by different chemical approaches. The efficacy of these nanoparticles was carried out by cell vi...