OBJECTIVE Thymocyte apoptosis is a major event in sepsis; however, how this process is regulated remains poorly understood. APPROACH AND RESULTS Septic stress induces glucocorticoids production which triggers thymocyte apoptosis. Here, we used scavenger receptor BI (SR-BI)-null mice, which are completely deficient in inducible glucocorticoids in sepsis, to investigate the regulation of thymoc...

The ongoing high relevance of business intelligence (BI) for the management and competitiveness of organizations requires a continuous, transparent, and detailed assessment of existing BI solutions in the enterprise. This paper presents a BI maturity model (called biMM) that has been developed and refined over years. It is used for both, in surveys to determine the overall BI maturity in German...

This chapter introduces the role of Data Mining (DM) for Business Intelligence (BI) in Knowledge Management (KM), thus explaining the concept of KM, BI, and DM; the relationships among KM, BI, and DM; the practical applications of KM, BI, and DM; and the emerging trends toward practical results in KM, BI, and DM. In order to solve existing BI problems, this chapter also describes practical appl...

BACKGROUND Body image (BI) is a multidimensional construct that includes perceptual, attitudinal, behavioural components, and feedback from other people's perception of oneself. The feedback from others and the degree to which one accepts or rejects it can determine self evaluation and perception. Body weight perception is a strong determinant of nutritional habits and weight management among a...

Although native bismuth is a relatively common mineral, native antimony is less abundant, and Sb-Bi alloys are relatively rare phases in Nature. Sb-Bi alloys and Ag-Cu-Pb-Sb-Bi sulphosalts have been discovered in the Jialong vein-type Cu-Sn deposit in North Guangxi, South China. The Jialong deposit is hosted by schist within the contact zone of a Neoproterozoic granite. Four stages of ore forma...

Hepatitis C virus (HCV) enters cells via a pH- and clathrin-dependent endocytic pathway. Scavenger receptor BI (SR-BI) and CD81 are important entry factors for HCV internalization into target cells. The SR-BI gene gives rise to at least two mRNA splice variants, SR-BI and SR-BII, which differ in their C termini. SR-BI internalization remains poorly understood, but SR-BII is reported to endocyto...

Bi(2)SbVO(7) was prepared by solid-state reaction technique for the first time and the structural and photocatalytic properties of Bi(2)SbVO(7) and Bi(2)GaTaO(7) were investigated. The results showed that Bi(2)SbVO(7) crystallized with the tetragonal crystal system by space group I4/mmm. In addition, the band gaps of Bi(2)SbVO(7) and Bi(2)GaTaO(7) were estimated to be 2.33 and 2.52 eV. The phot...

Implementation of a business intelligence (BI) system requires considerable resources. Although, the BI market appears vibrant and the importance of BI is widely accepted, few studies have investigated the Critical Success Factors (CSF) that affects its successful implementation. There is an imperative for a CSF approach to enable BI stakeholders to focus on the key issues that lead to successf...

this paper proposes a bi-objective model for the facility location problem under a congestion system. the idea of the model is motivated by applications of locating servers in bank automated teller machines (atms), communication networks, and so on. this model can be specifically considered for situations in which fixed service facilities are congested by stochastic demand within queueing frame...