We present the case of an anomalous origin of the left anterior cerebral artery (ACA) from the supraclinoid segment of the right internal carotid artery. Because of improved imaging quality, anomalies of the ACA-anterior communicating artery (AComA) complex are increasingly recognized on transaxial images. Although most of these anomalies are incidental findings of little clinical significance,...

BACKGROUND If successfully implemented and enduring, the Affordable Care Act (ACA) stands to expand health insurance access in absolute terms, reduce inter-group disparities in that access, and reduce exposure to the financial vulnerabilities illness entails. Its durability--meaning both avoidance of outright retrenchment and fidelity to its policy aims--is thus of scholarly interest. Past lite...

The objective of this study is to determine whether patients with systemic lupus erythematosus (SLE) and anticardiolipin antibodies (ACA) have biochemical evidence of an ongoing prothrombotic state. Using a cross-sectional analysis of a cohort design in an outpatient SLE clinic setting, 43 consecutive patients with SLE participated. Patients underwent clinical and laboratory evaluations on two ...

The standard enzyme-linked immunosorbent assay (ELISA) for anticardiolipin antibodies (ACA) detects a heterogenous group of antibodies against cardiolipin on its own, b2glycoprotein I (b2GPI), and, potentially, other phospholipidbinding plasma proteins from bovine or human origin. In an attempt to identify new proteic targets of ACA, we selected 6 patients who possessed cofactor-dependent ACA b...

Pseudouridylation, the isomerization of uridine to pseudouridine, is the most frequent post‐ transcriptional modification of RNA, such that pseudouridine has even been termed the fifth nucleotide. Whereas eubacteria employ single protein enzymes to identify and modify target uridines, archaebacteria and eukaryotes additionally evolved more complex modification machines, H/ACA ribonucleoproteins...

Zhuo JL, Carretero OA, Peng H, Li XC, Regoli D, Neugebauer W, Rhaleb NE. Characterization and localization of Ac-SDKP receptor binding sites using I-labeled Hpp-Aca-SDKP in rat cardiac fibroblasts. Am J Physiol Heart Circ Physiol 292: H984–H993, 2007. First published October 6, 2006; doi:10.1152/ajpheart.00776.2006.—We have shown that the tetrapeptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-S...

BACKGROUND Morbidity and mortality after resuscitation largely depend on the recovery of brain function. Ventricular fibrillation cardiac arrest (VFCA) and asphyxial cardiac arrest (ACA) are the two most prevalent causes of sudden cardiac death. Up to now, most studies have focused on VFCA. However, results from the two models have been largely variable. So, it is necessary to characterize the ...

CONTEXT The Patient Protection and Affordable Care Act (ACA) is changing the landscape of health systems across the United States, as well as the functioning of governmental public health departments. As a result, local health departments are reevaluating their roles, objectives, and the services they provide. OBJECTIVE We gathered perspectives on the current and future impact of the ACA on g...

A 76-year-old man presented with fluctuating right-hand clumsiness and mild right-leg weakness. MRI revealed a left anterior cerebral artery (ACA) infarct with perfusion/diffusion mismatch. Gradient echo imaging showed a left ACA clot, and magnetic resonance angiography showed left A2 occlusion (figure, A). The patient’s symptoms recurred the next morning, when mean arterial pressure (MAP) was ...

(ACA)-anterior communicating artery (AComA) complex are commonly identified at imaging studies, an infraoptic ACA is extremely rare (1-4). In such cases, an anomalous vessel originates from the internal carotid artery (ICA) at the level of the ophthalmic artery, and then pursues an infraoptic and prechiasmatic path to supply the ACA. We describe a case of in which this anomaly coexisted with a ...