We have developed a dual-component artificial nerve graft comprising an outer microporous conduit of chitosan and internal oriented filaments of polyglycolic acid (PGA). The novel graft was used for bridging sciatic nerve across a 30-mm defect in six Beagle dogs, which were used as a chitosan/PGA graft group. The other Beagle dogs were divided into an autograft group (n = 6) as the positive con...

The medial patellofemoral ligament (MPFL) has been recognized as an important soft tissue restraint in preventing lateral patellar translation. As many patients with acute or chronic patellar instability will have a deficient MPFL, reconstruction of this ligament is becoming more common. Appropriately, significant research has been undertaken regarding graft biomechanics and techniques, as intr...

OBJECTIVE Inflammation appears intricately linked to vein graft arterialization. We have previously shown that tumor necrosis factor (TNF) receptor-1 (TNFR1, p55) signaling augments vein graft neointimal hyperplasia (NH) and remodeling through its effects on vascular smooth muscle cells (SMCs). In this study we examined the role of TNFR2 (p75) signaling in vein graft arterialization. METHODS ...

We report a case of aortic stenosis with porcelain aorta using an apicoaortic valved conduit after 'aortic no touch' off-pump coronary artery bypass grafting. Apicoaortic valved conduit is a good surgical option for this patient to avoid re-entry through the sternum, injury to patent graft and manipulation of the porcelain ascending aorta.

BACKGROUND AND PURPOSE Substantial bone loss in revision total knee arthroplasty (TKA) is a challenging problem. We studied whether impaction bone grafting provides long-term restoration of bone stock in the treatment of major bone defects in revision surgery of rotational and hinged knee arthroplasties (LINK Endo-Model). PATIENTS AND METHODS Between 1996 and 2006, 29 knees in 29 patients und...

A GREAT number of histological studies on corneal grafts are to be found in the current literature. In very few of these, however, has any attention been paid to the nerves. Only a few authors have used nerve stainings. The present investigation has been made with the object of seeing whether any defects in the regeneration of the corneal nerves could have to do with the clouding of the grafts....

PurposeTransplant center volume is associated with improved survival after isolated heart transplant, but its impact on multiorgan transplant outcomes unknown. This study examines the of institutional outcomes.MethodsAdult patients undergoing first time from 2011-2021 were identified in United Network for Organ Sharing database. For each year, centers classified as low-, medium-, or high-volume...

it is difficult to reconstruct an alar defect with cartilage involvement. here in the authors report a case of traumatic alar loss during childhood in which an alar reconstruction was carried out with a composite auricular graft put over the pedicle buccal flap which was rotated and passed through the intraoral side. the lining skin and auricular cartilage for the flap was obtained from the aur...

PURPOSE To describe a novel, small-incision, no-fold Descemet stripping automated endothelial keratoplasty (DSAEK) graft injector and to compare complications, visual acuity, and endothelial cell loss with a forceps technique. METHODS An Institutional Review Board-approved, interventional, nonrandomized, consecutive case series analysis of 175 eyes undergoing DSAEK for Fuchs dystrophy and bul...