introduction: antibiotic resistance among bacteria in particular those producing extended spectrum beta lactamases (es- bls) has a very significant role in hospital acquired infections. some of the gram negative bacilli including klebsiella pneu- monia and escherichia coli are known to be esbl producers which cause uncontrollable infections because they are also often resistant to other antimic...

The Limulus amebocyte lysate (LAL) assay is a sensitive method for detecting endotoxin. Using gram-negative (GN) bacteremia as the basis for comparison, concordance with endotoxemia in 45 studies could be expressed as an odds ratio. Calculation of summary odds ratios by the Mantel-Haenszel-Peto method indicated that the concordance of the results was no higher by the chromogenic LAL assay than ...