The changing pattern of organisms causing neonatal sepsis, from Streptococcus pyogenes in the 1930s to Staphylococcus aureus in the 1950s and more recently to Gram negative bacilli and the group B streptococcus,' has been reflected in the development of new antibiotics. In particular semi-synthetic penicillins and the so called third generation cephalosporins have been introduced, both with act...

Purpura fulminans is a hemorrhagic condition associated predominantly with meningococcal and other gram negative septicemias. It occurs mainly in infants and younger children. Features include tissue necrosis, small vessel thrombosis, disseminated intravascular coagulation, multi-organ failure and death. Other causes include clotting factor deficiencies and idiopathic varieties. The condition i...

Severe sepsis is a leading cause of death in the United States and the most common cause of death among critically ill patients in non-coronary intensive care units (ICU). Respiratory tract infections, particularly pneumonia, are the most common site of infection, and associated with the highest mortality. The type of organism causing severe sepsis is an important determinant of outcome, and gr...

Epidemiology and surveillance of neonatal sepsis helps in implementation of rational empirical antibiotic strategy. The present study was conducted to record the frequency of bacterial isolates of neonatal sepsis and their sensitivity pattern in neonates treated in our tertiary care NICU. In this retrospective study, neonates in whom neonatal sepsis was suspected and blood culture done were inc...

background: urinary tract infection (uti) is considered as the most common bacterial infectious disease seen among the pediatric patients. the aim of this study was to investigate the prevalence and antimicrobial susceptibility of bacterial uropathogens isolated from the pediatric patients with urinary tract infections. methods: this descriptive study was conducted in children medial center, te...

Severe sepsis refers to the syndrome of fever, hypotension and organ dysfunction resulting from infection, commonly due to Gram-negative or Gram-positive bacteria with or without bacteraemia1. Occasionally, non-bacterial pathogens, including fungi, rickettsiae, protozoa and viruses, can cause a similar syndrome. The first line of defence against infecting organisms comprises highly conserved in...