In this chapter, we embark on a more specific granulation theory, stemming from the mereological theory of things. This mechanism provides us with tolerance and weak tolerance relations forming a graded similarity in the sense of Chap.1 and with resulting therefrom granules. To put the necessary notions in a proper order, we are going to discuss mereology, rough mereology and the mereological g...

This work describes a melt granulation technique to improve the solubility and dissolution characteristics of a poorly water-soluble drug Fenofibrate (FNO). Melt granulation technique is a process by which pharmaceutical powders are efficiently agglomerated by a meltable polymers and surfactants. The advantage of this technique compared to a conventional granulation is that no water or organic ...

OBJECTIVE To investigate the wound-healing properties of crude bark extract of Jatropha curcas Linn in Wistar albino rats. METHODS This work was carried out in the Department of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India, in the year 2005. We divided the animals into 3 groups of 12 each. Group I was saline control without wound, grou...

Context. Local-box hydrodynamical model atmospheres provide statistical information about a star's emergent radiation field which allows one to predict the level of its granulation-related micro-variability. Space-based photometry is now sufficiently accurate to test model predictions. Aims. We aim to model the photometric granulation background of HD 49933 as well as the Sun, and compare the p...

BACKGROUND Therapeutic effects of various treatment options in burn wound healing have been one of the most controversial issues in wound care. Aloe Vera is an herbal medicine, which has wound healing effects on chronic wound. The present study was carried out to examine and compare the effect of Aloe Vera gel and nitrofurazone 2% on epithelialization and granulation tissue formation with respe...

Benign airway stenosis is a clinical challenge because of recurrent granulation tissues. Our previous study proved that a Chinese drug, β-elemene, could effectively inhibit the growth of fibroblasts cultured from hyperplastic human airway granulation tissues, which could slow down the progression of this disease. The purpose of this study is to find out the mechanism. We cultured fibroblasts fr...

During the healing of an experimental skin wound, epidermal cells and granulation tissue fibroblasts (myofibroblasts) develop an extensive cytoplasmic contactile apparatus. Concurrently, the proportion of epidermal cell surface occupied by gap junctions increases when compared to normal skin, and newly formed gap junctions appear between myofibroblasts; this suggests that epidermal cell migrati...