نتایج جستجو برای: granulocyte colony

تعداد نتایج: 64612  

2003
Zeev Estrov Razelle Kurzrock Meir Wetzler Hagop Kantarjian Mary Blake David Harris Moshe Talpaz

In this study, we investigated the role of interleukin-lp (IL-1s) in the malignant evolution of chronic myelogenous leukemia (CML) and the functional activity of IL-1 inhibitors. Bone marrow (BM) and peripheral blood (PB) low-density cells from 38 CML patients were studied in the colonyforming unit-granulocyte, erythrocyte, monocyte, megakaryocyte colony culture assay. Samples from patients wit...

Journal: :Blood 1993
T J Brown J Liu C Brashem-Stein M Shoyab

Oncostatin M (OM) is structurally and functionally related to a subclass of hematopoietic cytokines including leukemia-inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), granulocyte colony-stimulating factor (G-CSF), and interleukin-6 (IL-6). Using human endothelial cells (HEC) as a model for cytokine regulation of hematopoietic growth factor expression, we tested OM as an inducer of ...

Journal: :Blood 1990
G K Sing F W Ruscetti

The pathogenic effects of human cytomegalovirus (CMV) infection in vitro on hematopoiesis were investigated. Normal human bone marrow cells from both seronegative and seropositive donors were challenged with CMV (Towne or wild-type strain) and tested for their responsiveness to the recombinant hematopoietic growth factors granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte...

Journal: :Cancer research 1990
M Wetzler R Kurzrock K Taylor G Spitzer H Kantarjian G Baiocchi S Ku J U Gutterman M Talpaz

Study of growth factor RNA levels in the stromal cells derived from the adherent layer of long-term bone marrow culture demonstrated constitutive expression of transforming growth factor beta 1 (TGF-beta 1) and macrophage colony-stimulating factor. These cells did not express granulocyte colony-stimulating factor, granulocyte-monocyte colony-stimulating factor, interleukin (IL) 1 alpha, IL-1 be...

Journal: :Proceedings of the National Academy of Sciences 1994

Journal: :The Journal of clinical investigation 1980
J W Adamson J W Singer P Catalano S Murphy N Lin L Steinmann C Ernst P J Fialkow

Further in vitro studies of hematopoietic regulation were carried out in two patients with polycythemia vera who were also heterozygotes (Gd(B)/Gd(A)) for glucose-6-phosphate-dehydrogenase (G-6-PD). While only G-6-PD type A was detectable in circulating erythrocytes, granulocytes and platelets, cultures of peripheral blood and marrow from one patient revealed a substantial number of G-6-PD type...

Journal: :International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2019

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