OBJECTIVE Graves' disease and Hashimoto's thyroiditis are the most common causes of hyper and hypothyroidism, respectively. Differentiation of these 2 diseases, if the patient is euthyroid, may sometimes be extremely difficult on the basis of clinical and laboratory findings. The purpose of this study was to determine the sensitivity and specificity of gray scale sonography in differentiation o...

The aim of the present study was to investigate the prevalence of antipituitary antibodies (APA) in patients with autoimmune thyroid disease as determined by Western blot analysis and enzyme-linked immunosorbent assay (ELISA). Results by Western blot analysis showed positivity for APA in serum of 22.4% of patients with Graves' disease (n= 143, p<0.05) and 18.5% of patients with Hashimoto's thyr...

Reactive C-cell hyperplasia (CCH) has been observed in cases of autoimmune Hashimoto's thyroiditis; however, its occurrence in Graves' disease, the other major autoimmune disorder, has not yet been investigated. On the other hand, although Carcinoembryonic Antigen (CEA) serum levels have been reported elevated in patients with autoimmune thyroid disease (ATD), the source of CEA production at th...

Abstract Introduction The impact of thyroidectomy for Graves’ disease (GD) on ophthalmopathy (GO) is not well understood. It generally accepted that does exacerbate or precipitate GO in the majority. aim this study was to evaluate whether prophylactic glucocorticoid use following total GD prevents early post-operative reactivation GO. Methods A retrospective cohort covering 5 years, studying pa...