The history of RIPs, especially the toxic ones, has been well reviewed recently. This present chapter will summarize the research steps that in the last 40 years have led to significant advancements in the knowledge of these proteins, of their mechanism of action, and of their possible practical applications in medicine and in agriculture. Ribosome-inactivating proteins (RIPs), initially discov...

Inhalational insulin was withdrawn from the market due to its potential to produce airway hyper-reactivity and bronchoconstriction. So the present study was designed to explore the acute effects of insulin on airway reactivity of guinea pigs and protective effects of salbutamol and beclomethasone against insulin induced airway hyper-responsiveness on isolated tracheal smooth muscle of guinea pi...

The objective of the present work was to register the first proven cases of human pseudomyiasis due to Eristalis tenax in Goiás State, Brazil, underscoring their clinical manifestations and direct relationship with hygiene. The taxonomic identification of the instars was done according to the descriptions and keys presented by James (1947), Hartley (1961) and Guimarães & Papavero (1999). Two ca...

Length The structured abstracts were, as expected, longer than the traditional ones. Indeed, they were approximately 30 percent longer, which is 10 percent more than the average 20 percent increase in length reported by Hartley (2002) for nine studies. It is interesting to note, however, that the average Hartley / CLARITY OF JOURNAL ABSTRACTS IN PSYCHOLOGY 371 TABLE 2 The Average Scores and Sta...

4. Buehler JW, Berkelman RL, Hartley DM, Peters CJ. Syndromic surveillance and bioterrorism-related epidemics. Emerg Infect Dis. 2003;9:1197–204. 5. Centers for Disease Control and Prevention. In the absence of SARS-CoV transmission worldwide: guidance for surveillance, clinical and laboratory evaluation, and reporting, version 2; January 21, 2004. [cited 2003 Jun 2]. Available from: http://www...

FEMALE GUINEA PIGS WERE INJECTED WITH THE FOLLOWING MATERIALS: homogenates of guinea pig testis in saline or in adjuvant; suspensions of washed guinea pig sperm in saline or in adjuvant; homogenates of rabbit testis in adjuvant; guinea pig sperm and rabbit sperm in adjuvant. Control animals were not injected or were injected with adjuvant alone. At various times between 15 and 39 days after inj...

Fibrinogen synthesis was investigated in guinea pig megakaryocytes. Purified megakaryocytes were incubated with 35S-methionine in methionine-free incubation medium for 18 hours. Newly synthesized fibrinogen in megakaryocyte lysates enriched with purified carrier guinea pig fibrinogen was immunoprecipitated with a specific anti-guinea pig fibrinogen antiserum produced in rabbits. Proteins in the...

In I9O 7, Sachs and Teruuchi 1 reported that if fresh guinea pig serum were appropriately diluted with distilled water (optimum relationship, I part serum to 8 to 9 parts distilled water), and incubated for an hour or more in a water bath at 37 ° C., on the restoration of isotonicity, complement activity no longer took place. The absence of hemolysis they attributed to a permanent' destruction ...

Ouabain-sensitive K influx into ground squirrel and guinea pig red cells was measured at 5 and 37 degrees C as a function of external K and internal Na. In both species the external K affinity increases on cooling, being three- and fivefold higher in guinea pig and ground squirrel, respectively, at 5 than at 37 degrees C. Internal Na affinity also increased on cooling, by about the same extent....

A cytokine that inhibits fibrinolysis has been detected in the serum-free culture medium of guinea pig and hamster fibroblasts. This proteinase inhibitor was also present in Triton X-100 extracts of guinea pig cells. It was stable at pH 3.0 for 2 hr and was produced by cells rather than assimilated from serum in the culture medium as evidenced by: (a) an apparent molecular size (less than 45 ki...