Acetaminophen (AAP) overdose causes formation of peroxynitrite in centrilobular hepatocytes. Treatment with glutathione (GSH) after AAP accelerated recovery of mitochondrial GSH levels, which scavenged peroxynitrite and protected against liver injury at 6 h. The objective of this investigation was to evaluate whether GSH treatment has a long-term protective effect against AAP-induced injury and...

H was intentionally incorporated into as-deposited ZnO films by plasma exposure treatment. The resistivity of ZnO films was reduced to the order of 10(-3) Ω cm after H plasma treatment, and high conductive stability was identified using a post-annealing process. To find an explanation for the stable conductivity, first-principle calculation was performed. Results predicted that H atoms trapped ...

the aim of this study was to characterize the effect of typhoid fever on pharmacokinetic parameters of levofloxacin (lf) and compare the pharmacokinetic parameters of the said antibiotic in healthy human volunteers and patients with typhoid fever. total of 12 subjects were divided into two groups “a” (healthy volunteers) and “b” (typhoid patients). single oral dose of lf 500 mg was given and 5 ...

licorice is obtained from glycyrrhiza glabra (g. glabra) in iran. glycyrrhizin is the main constituent of g. glabra and has several pharmacological effects. it is hydrolyzed to glycyrrhetic acid (ga) in the intestine after oral administration. in this study, a novel hplc method was used to determine the concentration of ga in rat plasma after oral administration of licorice aqueous extract. the...

Recently non-thermal plasma (NTP) is applied for many therapeutic applications. By NTP irradiating to the tissues or cell-lines, the water molecules (H2O) would be also activated leading to generate hydrogen peroxide (H2O2). By irradiating plasma to bio-solution, its main output including vacuum UV to UV causes the photolysis of H2O leading to generat...

Newborn Holstein bull calves (n = 32) were assigned to receive a colostrum supplement (CS) containing defibrinated bovine plasma or a colostrum replacer (CR) containing an immunoglobulin concentrate obtained by concentrating the immunoglobulin (Ig)G fraction of bovine plasma. The CS and CR contained 11.1 and 21.2% of dry matter as IgG, respectively. Each animal was fed two 454-g feedings at 1 a...

The aim of this study was to characterize the effect of typhoid fever on pharmacokinetic parameters of levofloxacin (LF) and compare the pharmacokinetic parameters of the said antibiotic in healthy human volunteers and patients with typhoid fever. Total of 12 subjects were divided into two groups “A” (healthy volunteers) and “B” (typhoid patients). Single oral dose of LF 500 mg was given and 5 ...

Plasma agriculture has been considered as a promising solution for sustainable and safe agri-food production. Its applications include germination induction, plant-growth stimulation, post-harvest sterilization management. For growth both direct indirect have widely studied. plasma application, plasma-activated medium largely tested its uses in plant This study preliminarily reports the diffusi...

This study examined the effects of dexamethasone treatment on basal hypothalamo-pituitary-adrenal (HPA) axis function and HPA responses to subsequent acute hypoxemia in the ovine fetus during late gestation. Between 117 and 120 days (term: approximately 145 days), 12 fetal sheep and their mothers were catheterized under halothane anesthesia. From 124 days, 6 fetuses were continuously infused in...