A history of previous birth of a low birthweight infant, previous cesarean sections, multiple previous spontaneous abortions, prior stillbirth, or uterine anomaly identifies women at increased risk for recurrent abortion, preterm birth, or stillbirth. We review the evidence for the potential benefit of reproductive history in identifying strategies for evaluation and treatment to prevent recurr...

OBJECTIVE The purpose of this study was to determine the frequency and distribution of cytogenetically abnormal miscarriages in couples with spontaneous abortions (SA) or recurrent miscarriages (RM). METHODS Karyotyping of specimens from 164 abortuses with SA and 86 abortuses with RM was successfully performed according to the standard cytogenetic methods using G-banding technique. RESULTS ...

Background: Listeria monocytogenes is the causative agent of listeriosis, a highly fatal opportunistic food borne infection. Listeriolysin O is a major virulence factor in this bacterium, which is encoded by hlyA. The aim of the present study was to determine the relation of Listeria monocytogenes hlyA gene isolated from fresh cheese with habitual abortion in Marvdasht. Materials and methods: I...

1 Warburton D, Fraser FC. Spontaneous abortion risks in man: data from reproductive histories collected in a medical genetics unit. flum Genet 1964;16: 1-25. 2 Huisies HJ. Spontaneous abortion. Edinburgh: Churchill Livingstone, 1984. 3 Malpas P. A study of abortion sequences.journal oJfObstetrics and GYnttaecologv ofthe British Empire 1938;45:932-49. 4 Naylor AF. Sequential aspects of spontaneo...

Background: The role of subchorionic hematoma (SCH) in the first trimester of pregnancy remains open for discussion. Some authors claim that SCH does not affect the pregnancy; others have found that it is a serious risk factor for adverse pregnancy outcome. The objective of the present study was to explore the outcomes of pregnancy in patients with SCH diagnosed in the first trimester. Methods ...

BACKGROUND Couples with recurrent miscarriages make several visits to specialized clinics for investigations before treatment is offered. Consequently, 'the interval' between receipt of referral and advice to try for a pregnancy is often lengthy. The objectives of this study were to examine the effect of a 'one-stop' clinic on 'the interval', throughput and the outcome from this clinic. METHO...

Recurrent miscarriages are one or more pregnancy losses before 20-24 weeks of gestation or below a fetal weight of 500 g (Pic. 1). About 1% of women in reproductive age are affected by recurrent miscarriages. The majority of patients are counseled to try to conceive again, and chances are about 60% that the next pregnancy is successful without treatment. However, each additional loss worsens th...

While it has been established that anti-phospholipid antibodies (aPL) are associated with recurrent miscarriage (RM), the importance of anti-beta2 glycoprotein 1 (GP1) IgG and anti-annexin V IgG antibodies as risk factors for RM is undefined. We have investigated the prevalence of anti-beta2 GP1 IgG and anti-annexin V IgG antibodies in 54 aPL-positive and 48 aPL-negative women with RM. The prev...