OBJECTIVE To find the prevalence of psychiatric disorders among the opioids dependents and to assess the severity of their addiction profile. METHOD Sample comprised of fifty patients admitted in drug treatment and rehabilitation center at Psychiatry Department of Lady Reading Hospital, Peshawar, between March to August 1997. DSM-IV diagnostic criteria were applied to diagnose substance depen...

BACKGROUND Frozen shoulder is resulting in limb disability and reduction of quality of life but the factors associated with patients' disability and quality of life is not clear. To assess pain, disability, the quality of life and factors associated with them in patients suffering from frozen shoulder. METHODS We enrolled 120 patients (37 men and 83 women) with phase-II idiopathic frozen shou...

Efficacy of centpropazine, a new antidepressant, has been evaluated in forty two patients of endogenous depression. The 4 week open trial was carried out in a dose-range of 40 to 120mg per day. A significant lowering of Hamilton Depression Rating Scale (HDRS) score was observed in 34 patient. The antidepressant effect could be detected in 9 patients within one week, in 28 cases in two weeks and...

One hundred patients of Diabetes Mellitus (30 insulin dependent and 70 non-insulin dependent) were studied for frequency and severity of depressive symptoms. The subjects were evaluated on Schedule for Standardised Assessment of Affective Disorder (SADD) and Hamilton Rating Scale for Depression (HRSD).Result show that symptoms such as depressed mood-decreased work and activities and loss of wei...

AIM The objective of this study was to analyze the changes in depressive and extrapyramidal symptomatology during glycine augmentation of antipsychotic treatment in patients with schizophrenia. MATERIALS AND METHODS Twenty-nine schizophrenic patients (ICD-10) with predominant negative symptoms in stable mental state participated in a 10-week open-label prospective study. Patients received sta...

s: Purpose: This study aims to evaluate the effect of psychological counseling combined with auricular plaster therapy in treating the elderly patients with anxiety disorders. Methods: 36 elderly patients with anxiety disorders were divided into experimental group and control group at random, with each group including 18 patients. The control group was only treated with psychological counseling...

BACKGROUND Patients with affective disorders of different ages have been found to present weight changes and different circadian activity patterns. This study assessed the effects of age, Body Mass Index (BMI) and depression severity on the activity-rest cycle in persons with affective disorders using a novel multifactorial 24-h analysis method. METHODS Two hundred and thirty-six participants...

BACKGROUND There is an established relationship between depression/anxiety disorders and cardiovascular morbidity and mortality which has been previously documented. However, there has been no study evaluating coronary slow flow in association with depression and anxiety. METHODS AND RESULTS A total of consecutive 90 patients were included in the study. All patients completed scoring scales f...

BACKGROUND In schizophrenia and major depressive disorder, anhedonia (a loss of capacity to feel pleasure) had differently been considered as a premorbid personological trait or as a main symptom of their clinical picture. The aims of this study were to examine the pathological features of anhedonia in schizophrenic and depressed patients, and to investigate its clinical relations with general ...

BACKGROUND Proper management of depression in elderly population would improve the outcome of the disease and reduce its related disability and mortality. Use of memantine with minimal side effects and drug interaction seems reasonable in the elderly but its antidepressant activity is controversial. The aim of the current research is to investigate the effects of add-on memantine during citalop...