BACKGROUND AND PURPOSE We studied the value of clinical and electroencephalographic assessment in patients with acute first-ever supratentorial ischemia in predicting functional outcome after 1 year. METHODS In 55 consecutive patients admitted after a median interval of less than 24 hours, the degree of handicap was dichotomized as moderate (Rankin grade 1, 2, or 3) or severe (Rankin grade 4 ...

A particular game-theoretic model (Grafen, 1990) of the evolutionary stability of honest signalling, which attempts a formal proof of the validity of Zahavi's (1975, 1977) handicap principle, is generalised and rendered as an evolutionary simulation model. In addition to supporting new theoretical results, this allows the eeects of diiering initial conditions on the attainability of signalling ...

iran is a large country with a total area of 1,645,000 square kilometers. the country’s population is estimated at about 31 millions. there is an uneven distribution of the population, varying from 2 to 50 per square kilometer. sixty per cent of the total population (18 millions) is living in nearly 66,000 small and large village’s scattered throughout the country. a total of 10,000 physicians ...

background: dizziness as a common symptom affecting many aspects of the patient’s life and it is hard to be fully evaluated. the dizziness handicap inventory (dhi) is a reliable self-perceived questionnaire in the evaluation of dizziness impacts. the purposes of this study are translation of the dhi to persian language and measuring its psychometric properties, including face, content, discrimi...

The Handicap Principle represents a central theory in the biological understanding of signaling. This paper presents a number of alternative theories to the Handicap Principle and argues that some of these theories may provide a better explanation for the evolution and stability of honest communication.

We report a mother and son who each presented in infancy with hypotonia and global developmental delay. Subsequently, in both subjects, mild mental handicap was diagnosed in association with temporal lobe arachnoid cysts. Mendelian inheritance of this phenotype seems likely and macroscopic cerebral dysplasia in general may be underdiagnosed in people with familial, mild mental handicap.

more and more first-class entrants. We must have more teachers, more nurses, more scientists, and so on, and they must all be of the first rank. One is sometimes tempted to wonder whether there really are enough highly intelligent people to go round. We certainly cannot afford to waste any of them, and we ought perhaps to spend rather more time considering them and their needs than we do. They ...

BACKGROUND Although voice tremor is one of the most commonly noted clinical features of essential tremor (ET), there are nearly no published data on the handicap associated with it. METHODS The Voice Handicap Index (VHI) was self-administered by participants enrolled in a research study at Columbia University Medical Center. The VHI quantifies patients' perceptions of handicap due to voice di...