نتایج جستجو برای: hat1

تعداد نتایج: 133  

Journal: :The Journal of biological chemistry 2010
Jian-Qiang Chen Yang Li Xian Pan Bing-Kun Lei Cheng Chang Zheng-Xun Liu Hong Lu

In budding yeast and human cells, ING (inhibitor of growth) tumor suppressor proteins play important roles in response to DNA damage by modulating chromatin structure through collaborating with histone acetyltransferase or histone deacetylase complexes. However, the biological functions of ING family proteins in fission yeast are poorly defined. Here, we report that Png1p, a fission yeast ING h...

2002
Sjef Smeekens Hanjo A. Hellmann

Sugars are ubiquitous and critical components for general metabolism. These primary products from photosynthesis affect most, if not all, processes in plant cells by providing skeletons for organic compounds and storing energy for chemical reactions. Sugars also serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response (Rolland et...

2012
Daniel Rathmann Diana Lindner Stephanie H. DeLuca Kristian W. Kaufmann Jens Meiler Annette G. Beck-Sickinger

The prolactin-releasing peptide receptor (PrRPR) and its bioactive RF-amide peptide (PrRP20) have been investigated to explore the ligand binding mode of peptide Gprotein coupled receptors (GPCR). By receptor mutagenesis we identified the conserved aspartate in the upper part of transmembrane helix 6 (D) of the receptor as the first position that directly interacts with arginine 19 of the ligan...

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