OBJECTIVE Estrogen seems to contribute to glucose homeostasis in women. The objective of this study was to examine the effects of hormone replacement therapy (HRT) on HbA(1c) levels in Japanese postmenopausal women and to determine whether the effects varied with age. RESEARCH DESIGN AND METHODS We studied 99 postmenopausal women taking HRT (mean +/- SD age 56.5 +/- 6.9 years, BMI 21.5 +/- 2....

OBJECTIVE Glycosylated hemoglobin (HbA(1c)) recently has been recommended for the diagnosis of diabetes by the American Diabetes Association, but its value in the prediction of type 2 diabetes is poorly understood. In this study we evaluated how high-normal HbA(1c) levels predict type 2 diabetes. RESEARCH DESIGN AND METHODS We measured HbA(1c) in 919 Caucasian subjects, aged 40-79 years, and ...

OBJECTIVE To test adherence to blood glucose monitoring (BGM) as a mediator between diabetes-specific family conflict and glycemic control (hemoglobin A(1c) [HbA(1c)] levels) for 1 year. DESIGN Three waves of prospective data spanning 1 year. SETTING Diabetes clinic in a large tertiary care children's hospital in the Midwestern United States. PARTICIPANTS One hundred forty-five dyads comp...

OBJECTIVE This study evaluated the risk of myocardial infarction (MI) by impaired glycemic control in a contemporary large cohort of patients with type 2 diabetes followed from diagnosis. RESEARCH DESIGN AND METHODS Patients with type 2 diabetes diagnosed between 1995 and 2011 were retrieved from the Clinical Practice Research Datalink in the U.K., and followed from diagnosis until event of M...

OBJECTIVE In type 2 diabetes, therapies to maintain blood glucose control usually fail after several years. We estimated the glycemic burden that accumulates from treatment failure and describe the time course and predictors of failure. RESEARCH DESIGN AND METHODS A prospective, population-based study using retrospective observational data. We identified all 7208 complete courses of treatment...

T he association between glycated he-moglobin (HbA 1c) and long-term diabetes complications is well established (1). Although HbA 1c is a key process and outcome measure in clinical and research settings, reporting varies from single annual measurements to an average of interval measurements per year. Seasonal HbA 1c variability within an individual may impact on audit and intervention studies ...

In order to effectively extract the characteristic information of bearing vibration signals and improve classification accuracy, a composite fault diagnosis method rolling based on chaotic honey badger algorithm (CHBA), which optimizes variational mode decomposition (VMD) extreme learning machine (ELM), is proposed in this paper. Firstly, aiming solve problem that HBA optimization process can e...

OBJECTIVE Diabetes and hypertension often co-occur and share risk factors. Hypertension is known to predict diabetes. However, hyperglycemia also may be independently associated with future development of hypertension. We investigated glycated hemoglobin (HbA(1c)) as a predictor of incident hypertension. RESEARCH DESIGN AND METHODS We conducted a prospective analysis of 9,603 middle-aged part...

OBJECTIVE We studied a systematic program to reeducate our medical house officers on how to manage inpatient hyperglycemia without the use of sliding-scale insulin (SSI). RESEARCH DESIGN AND METHODS Patients admitted to the general medical service with diabetes or a blood glucose >140 mg/dl were included. HbA(1c) was measured in all patients, and therapy was modified if the HbA(1c) was >7.0%....

We enzymatically modified rice starch to produce highly branched amylopectin and amylose and analyzed the resulting structural changes. To prepare the highly branched amylopectin cluster (HBAPC), we first treated waxy rice starch with Thermus scotoductus alpha-glucanotransferase (TSalphaGT), followed by treatment with Bacillus stearothermophilus maltogenic amylase (BSMA). Highly branched amylos...