Background: In spite of available, and sensitive screening assay for detection of hepatitis B virus surface antigen (HBsAg), occasional cases of post-transfusion hepatitis B virus infection are still observed. The aim of the present study was to assess the prevalence of positive anti hepatitis B core (anti-HBc) and presence of HBV-DNA in serum sample of healthy blood donors negative for both HB...

The aim of the current study was to evaluate viral suppression following combined treatment with an S/pre-S1/pre-S2 vaccine and lamivudine in patients with chronic hepatitis B. We established a randomized, controlled clinical trial to compare the responses of three different treatment groups: those receiving vaccine monotherapy, lamivudine monotherapy, or combination treatment. Viral response w...

HBV is a member of Hepadnavirus genus. HBV is a DNA virus with a diameter of 42 nm consisting of an outer lipid envelope which contains proteins HBsAg, pre-S1 and pre-S2. HBsAg is a product of ‘s’ gen. The s geneinvolves ‘a’ epitope124. -147. codones and this region is the affecting region for anti-HBs antibody binding. Vaccine /Immunglobulin escape mutations occur at HBV DNA s gene’s ‘a determ...

1Ministry of Labour and Social Security, Ankara, Turkey (Correspondence to R. Güven: [email protected]). 2Department of Public Health, Faculty of Medicine, Hacettepe University, Ankara, Turkey. Received: 17/02/04; accepted: 11/04/05 ABSTRACT Turkey is an intermediate endemic area for hepatitis B virus infection. The study investigated the hepatitis B exposure risk and prevalence of hepatitis B...

BACKGROUND There is a controversy about the relation between anti-hepatitis B (anti-HBs) antibody level and obesity. We designed this study to compare the vaccine efficacy in obese/overweight and non-obese cases. METHODS In this cross-sectional study, 242 obese/overweight and 85 non-obese individuals were participated. Cases were selected from a referral clinic for obesity and a referral hepa...

background: antibody production in patients with end-stage kidney disease impairs due to several mechanisms. there are different ways to improve response rate to hepatitis b (hb) vaccine. in this study we evaluated the effect of tetanus-diphtheria toxoid (td) vaccine on hbs antibody (ab) level while being given simultaneously with hb vaccine.  methods: we recruited 43 hemodialysis and 20 perito...

AIM This study was designed to evaluate the frequency of antibody against these viruses in individuals attending the endoscopy ward of Taleghani hospital Tehran, Iran. BACKGROUND Blood-borne viruses such as hepatitis B and hepatitis C virus and HTLV-1 virus are among the world's public health problems. Hepatitis viruses cause liver problems and HTLV-1 infection can lead to adult T-Cell lympho...

A study was conducted to determine the effect of the Candida albicans mannoprotein on Phagocytic activity, antibody production, serum gammaglobuline percentage and lymphocyte transformation index after vaccination with hepatitis B surface (HBs) antigen. It can be concluded that Mannoprotein isolated from Candida albicans cell wall are an important immunomodulatorts in the development of immune ...