Treatment of the internal mammary chain (IMC) with radiation therapy (RT) for patients with breast cancer remains a controversial issue. Different treatment techniques have been proposed, including oblique electrons, electron-photon combination, and partially wide tangents (PWTs). However, the residual heart dose can remain significant mainly for left-sided lesions. With PWTs and intensity-modu...

PURPOSE This study aims to compare the dosimetric data of local tumor's bed dose escalation (boost) with photon beams (external beam radiation therapy - EBRT) versus high-dose-rate interstitial brachytherapy (HDR-BT) after breast-conserving treatment in women with early-stage breast cancer. MATERIAL AND METHODS We analyzed the treatment planning data of 136 irradiated patients, treated betwee...

This study aims to evaluate the possibility of using the technique of volume-modulated arc therapy (VMAT) to combine the advantages of simplified intensity-modulated radiation therapy (sIMRT) with that of regular intensity-modulated radiation therapy (IMRT) in upper esophageal cancer. Ten patients with upper esophageal carcinoma were randomly chosen in this retrospective study. sIMRT, IMRT, and...

BACKGROUND Today it is unclear which technique for delivery of an additional boost after whole breast radiotherapy for breast conserved patients should be state of the art. We present a dosimetric comparison of different non-invasive treatment techniques for additional boost delivery. METHODS For 10 different tumor bed localizations, 7 different non-invasive treatment plans were made. Dosimet...

Iodine-125 ((125)I) and Caesium-131 ((131)Cs) brachytherapy have been used with sublobar resection to treat stage I non-small cell lung cancer and other radionuclides, (169)Yb and (103)Pd, are considered for these treatments. This work investigates the dosimetry of permanent implant lung brachytherapy for a range of source energies and various implant sites in the lung. Monte Carlo calculated d...

BACKGROUND This paper compares the calculated dose to target and normal tissues when using pencil beam (PBC), superposition/convolution (AAA) and Monte Carlo (MC) algorithms for whole breast (WBI) and accelerated partial breast irradiation (APBI) treatment plans. METHODS Plans for 10 patients who met all dosimetry constraints on a prospective APBI protocol when using PBC calculations were rec...

Radiotherapy plays an essential role in the management of breast cancer. Three-dimensional conformal radiation therapy (3D-CRT) is applied based on 3D image information of anatomy of patients. In 3D-CRT for breast cancer one of the common techniques is tangential technique. In this project, various parameters of tangential and supraclavicular fields are optimized. This project has been done on ...

Abstract Purpose Radiation therapy for mesothelioma remains challenging, as normal tissue toxicity limits the amount of radiation that can be safely delivered to pleural surfaces, especially dose contralateral lung. The physical properties proton result in better sparing tissues when treating pleura, both postpneumonectomy setting and lung-intact setting. Compared with photon radiation, there a...

background: the assessment of rbe quantity in the treatment of cancer tumors with proton beams in treatment planning systems (tps) is of high significance. given the significance of the issue and the studies conducted in the literature, this quantity is fixed and is taken as equal to 1.1. objective: the main objective of this study was to assess rbe quantity of proton beams and their variations...

We propose a comparative dosimetric study of whole-breast hypofractionated radiation therapy using helical tomotherapy (HT) in supine position and 3-D conformal radiotherapy (3D-CRT) in prone position. Twelve patients undergoing breast-conserving therapy were retrospectively selected from October to December 2012. Specific dose-volume parameters were selected for the study. The target coverage ...