In vitro sensitivity to porphyrin-mediated photodynamic therapy (PDT) has been examined in cell lines resistant to hyperthermia. Parental (1IA-1) and heat-resistant (3012) Chinese hamster fibroblasts as well as parental (RIF-1) and temperature-resistant (TR-4, TR-5, and TR-10) mouse radiation-induced fibrosarcoma cells were evaluated for thermal and PDT sensitivity. Quantitative survival curves...

Abstract Do changes in ocean heat transport (OHT) that occur with CO 2 forcing, impact climate sensitivity Earth system models? Changes OHT warming are ubiquitous model experiments: when forced , such models exhibit declining poleward both hemispheres at most latitudes, which can persist over multicentennial time scales. To understand how may the responds to particularly sensitivity, we perform...

Compensation of the poleward eddy heat transport by the heat transport of an eddy-induced mean meridional overturning cell is a common feature in many eddyresolving ocean models. It has been ,argued that this is the result of the weak thermal driving of the ocean. As the actual air/sea coupling is scale dependent, it might be questioned whether the approximation of weak thermal driving is relev...