Gap junctional communication modulates intercellular calcium signaling in many cell types. We have investigated whether gap junctional communication modulates calcium oscillatory behavior of cells responding to an agonist. Extracellular UTP induced calcium oscillations in 70% of HeLa cells cultured in monolayer, and neighboring cells oscillated independently of each other. In HeLa cell transfec...

objective: cervical cancer is the second most common cause of death from cancer in women throughout the world. the aim of this study was to evaluate the cytotoxic activity of kelussia odoratissima (k. odoratissima) extract associated with radiotherapy in cervical cancer cells (hela cell line).materials and methods: different concentration of the extract (25-500µg/ml) was tested in hela cell lin...

Combination of Cisplatin and Cinnamon Essential Oil Inhibits HeLa Cells Proliferation through Cell Cycle ArrestYonika Arum Larasati, Dyaningtyas Dewi Pamungkas Putri, Rohmad Yudi Utomo, Adam Hermawan, Edy Meiyanto

1. We have recently re-tested the STR fingerprinting data in our paper (Int J Biol Sci 2011; 7:892-901). DNA fingerprinting analysis was performed using genomic DNA from hsNSCs (passage 22); T1 cells (passages <50 and >150) and HeLa cells by GeneMapper ID v3.2 (Applied Biosystems, Foster City, CA) for human STR markers. There are two loci of heterozygosity CSF1PO (9, 10) and D3S1358 (15, 18) in...

Low power femtosecond-pulsed NIR irradiation kills HeLa cells incubated with Ag nanoplates by both photothermal effect and optical breakdown leading to plasma formation that spreads fast through the cell.

Tissue culture strains of cells from four different normal human tissues-liver, conjunctiva, kidney, and appendix-have been grown by the plating procedure previously developed for the HeLa strain of cervical carcinoma cells. This technique results in colony formation from isolated single cells, in a manner completely analogous to the plating of bacteria in semisolid nutrient media. Clonal cell ...

Abstract A large common species, Syzygium aqueum , belonging to the genus possesses numerous bioactive phytochemical constituents. Moreover, different parts of this species have been used as folk medicine since centuries ago. In study, a exploration was carried out on plant’s stem bark. Isolation compounds through extraction step with some organic solvents, followed by separation and purificati...

Our previous studies demonstrated that PML is a growth suppressor that suppresses oncogenic transformation of NIH/3T3 cells and rat embryo fibroblasts. PML is a nuclear matrix-associated phosphoprotein whose expression is regulated during the cell cycle. Disruption of PML function by t(15;17) in acute promyelocytic leukemia (APL) plays a critical role in leukemogenesis. To further study the rol...